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Title: | Effect of cafeteria diet feeding on soleus intramyocellular lipid of Wistar rats |
Author: | Cabot Majem, Cristina Pouillot, Karl Roy, Stéphanie Romero Romero, María del Mar Vilà Pont, Ruth Grasa Martínez, Maria del Mar Esteve Ràfols, Montserrat Fernández López, José Antonio Alemany, Marià, 1946- Remesar Betlloch, Xavier |
Keywords: | Dieta Lípids Músculs Mitocondris Teixit adipós Rates (Animals de laboratori) Diet Lipids Muscles Mitochondria Adipose tissues Rats as laboratory animals |
Issue Date: | Feb-2012 |
Publisher: | Elmer Press |
Abstract: | Background: The presence of lipid besides muscle fibres facilitates the energy supply for exercise, but it is also indicative of insulin resistance in the untrained. Muscle lipid is associated with increased dietary energy: hyperlipidic diets induce an increase in intramyocellular lipid deposition in skeletal muscle. Methods: In the present study we analyzed the changes in soleus (a red-fibre muscle) intracellular muscle content under a hyperlipidic (cafeteria) diet in Wistar rats. We also analyzed in parallel the mitochondrial content a relative index of energy output capability. Results: Cafeteria diet-fed rats contained more lipid and mitochondria per unit of muscle section area than controls. Conclusions: The correlation found in the increases of muscle lipid and mitochondria hit at this increase as an adaptation of muscle to oxidize excess energy substrates under conditions of excess energy availability, probably contributing to adaptive thermogenesis. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.4021/jem63w |
It is part of: | Journal of Endocrinology and Metabolism, 2012, vol. 2, num. 1, p. 21-25 |
URI: | http://hdl.handle.net/2445/53783 |
Related resource: | http://dx.doi.org/10.4021/jem63w |
ISSN: | 1923-2861 |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) Articles publicats en revistes (Institut de Biomedicina (IBUB)) |
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