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Title: Cyclosporine A, an alternative to the oral lichen planus erosive treatment
Author: López López, José, 1958-
Roselló Llabrés, Xavier
Keywords: Ciclosporina
Higiene bucal
Higiene dental
Mucosa oral
Oral hygiene
Dental hygiene
Oral mucosa
Issue Date: Jan-1995
Publisher: Groupement International pour la Recherche Scientifique en Stomatologie et Odontologie
Abstract: We present a double-blind study in two groups afflicted with oral lichen planus erythematous of long evolution and resistant to other treatments. We tested on it a treatment with Cyclosporine A (CyA) which had been successfully used before by many dermatologists. In the group A we used mouthwashes with a 5 ml Cyclosporine A solution to a 10% in olive oil of 0.4 degrees of acidity for five minutes, three times a day for eight weeks. In the control group we used acetonide of triamcinolone 01% in aqueous solution. Patients in group A improved considerably in their symptomatology in a 90% against a 60% in group B. In group A we could appreciate a disappearance of the symptomatology after two weeks of treatment in 60% of patients against 30% in group B. CyA can be an alternative to the conventional treatments in the acute period of lichen planus although it can not be considered as a first option drug because of the high cost of the treatment. For long term, results are not so good and we consider that extensive studies are necessary
Note: Reproducció del document publicat a:
It is part of: Bulletin du GIRSO, 1995, vol. 38, num. 1-2, p. 33-38
ISSN: 0250-4693
Appears in Collections:Articles publicats en revistes (Odontoestomatologia)

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