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DC Field | Value | Language |
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dc.contributor.author | Lanaspa, Miguel | - |
dc.contributor.author | O'Callaghan Gordo, Cristina | - |
dc.contributor.author | Machevo, Sonia | - |
dc.contributor.author | Madrid, Lola | - |
dc.contributor.author | Nhampossa, Tacilta | - |
dc.contributor.author | Acácio, Sozinho | - |
dc.contributor.author | Horra, C. de la | - |
dc.contributor.author | Friaza, Vicente | - |
dc.contributor.author | Campano, E. | - |
dc.contributor.author | Alonso, Pedro | - |
dc.contributor.author | Calderon, Enrique J. | - |
dc.contributor.author | Roca, A. | - |
dc.contributor.author | Bassat Orellana, Quique | - |
dc.date.accessioned | 2016-06-14T13:32:25Z | - |
dc.date.available | 2016-07-28T22:01:24Z | - |
dc.date.issued | 2015-07-28 | - |
dc.identifier.issn | 1198-743X | - |
dc.identifier.uri | http://hdl.handle.net/2445/99513 | - |
dc.description.abstract | We aimed to describe Pneumocystis jirovecii pneumonia (PCP) prevalence and features in children from sub-Saharan Africa, and to investigate PCP-associated risk factors. During 2006-2007 we used molecular methods to test children younger than 5 years old admitted with severe pneumonia to a hospital in Southern Mozambique for Pneumocystis infection. We recruited 834 children. PCP prevalence was 6.8% and HIV prevalence was 25.7%. The in-hospital and delayed mortality were significantly higher among children with PCP (20.8% vs. 10.2 %, p=0.021, and 11.5% vs. 3.6%, p=0.044, respectively). Clinical features were mostly overlapping between the two groups. Independent risk factors for PCP were age less than a year (OR 6.34, 95%CI 1.86-21.65), HIV infection (OR 2.99, 95%CI 1.16-7.70), grunting (OR 2.64, 95%CI 1.04-6.73), and digital clubbing (OR 10.75, 95%CI 1.21-95.56). PCP is a common and life-threatening cause of severe pneumonia in Mozambican children. Mother-to-child HIV transmission prevention should be strengthened. Better diagnostic tools are needed. | - |
dc.format.extent | 8 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | Elsevier | - |
dc.relation.isformatof | Versió postprint del document publicat a: http://dx.doi.org/10.1016/j.cmi.2015.07.011 | - |
dc.relation.ispartof | Clinical Microbiology and Infection, 2015, vol. 21, num. 11, p. 1018.e9–1018.e15 | - |
dc.relation.uri | http://dx.doi.org/10.1016/j.cmi.2015.07.011 | - |
dc.rights | cc by-nc-nd (c) European Society of Clinical Microbiology and Infectious Diseases, 2015 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | - |
dc.source | Articles publicats en revistes (ISGlobal) | - |
dc.subject.classification | Pneumònia | - |
dc.subject.classification | Infants | - |
dc.subject.other | Pneumonia | - |
dc.subject.other | Children | - |
dc.title | High prevalence of Pneumocystis jirovecii pneumonia among Mozambican children < 5 years of age admitted to hospital with clinical severe pneumonia | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.date.updated | 2016-06-13T15:59:43Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 26231980 | - |
Appears in Collections: | Articles publicats en revistes (ISGlobal) |
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lanaspa2015_1946.pdf | 448.51 kB | Adobe PDF | View/Open |
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