Browsing by Author Heyn, Holger

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Issue DateTitleAuthor(s)
3-Apr-2014A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effectLópez Serra, Paula; Marcilla, Miguel; Villanueva Garatachea, Alberto; Ramos Fernandez, Antonio; Palau, Anna; Leal, Lucía; Wahi, Jessica E.; Setién, Fernando; Szczesna, Karolina; Moutinho, Cátia; Martínez Cardús, Anna; Heyn, Holger; Sandoval, Juan; Puertas, Sara; Vidal-Bel, August; Sanjuan, Xavier; Martínez Balibrea, Eva; Viñals Canals, Francesc; Perales Losa, Carlos; Bramsem, Jesper B.; Ørntoft, Torben F.; Andersen, Claus L.; Tabernero Caturla, Josep; McDermott, Ultan; Boxer, Matthew B.; Vander Heiden, Matthew G.; Albar, Juan Pablo; Esteller, Manel
28-Jul-2016A landscape of pharmacogenomic interactions in cancerIorio, Francesco; Knijnenburg, Theo A.; Vis, Daniel J.; Bignell, Graham; Menden, Michael P.; Schubert, Michael; Aben, Nanne; Gonçalves, Emanuel; Barthorpe, Syd; Lightfoot, Howard; Cokelae, Thomas; Greninger, Patricia; Dyk, Ewald van; Chang, Han; Silva, Heshani de; Heyn, Holger; Deng, Xianming; Egan, Regina K.; Liu, Qingsong; Mironenko, Tatiana; Mitropoulos, Xeni; Richardson, Laura; Wang, Jinhua; Zhang, Tinghu; Moran, Sebastian; Sayols, Sergi; Soleimani, Maryam; Tamborero Noguera, David; López Bigas, Núria; Ross-Macdonald, Petra; Esteller, Manel; Gray, Nathanael S.; Haber, Daniel A.; Stratton, Michael R.; Benes, Cyril H.; Wessels, Lodewyk F. A.; Saez-Rodriguez, Julia; McDermott, Ultan; Garnett, Mathew J.
10-Nov-2013A prognostic DNA methylation signature for stage I non-small-cell lung cancerSandoval, Juan; Méndez González, Jesús; Nadal, Ernest; Chen, Guoan; Carmona, F. Javier; Sayols, Sergi; Moran, Sebastian; Heyn, Holger; Vizoso, Miguel; Gómez, Antonio; Sánchez Céspedes, Montserrat; Assenov, Yassen; Müller, Fabian; Bock, Christoph; Taron, Miquel; Mora, Josefina; Muscarella, Lucia A.; Liloglou, Triantafillos; Davies, Michael P. A.; Pollán, Marina; Pajares, María José; Torre, Wenceslao; Montuenga, Luis M.; Brambilla, Elisabeth; Field, John K.; Roz, Luca; Lo Iacono, Marco; Scagliotti, Giorgio V.; Rosell Costa, R.; Beer, David G.; Esteller, Manel
21-Sep-2021A single-cell tumor immune atlas for precision oncologyNieto, Paula; Elosua Bayes, Marc; Trincado, Juan L.; Marchese, Domenica; Massoni Badosa, Ramon; Salvany, Maria; Henriques, Ana; Nieto, Juan; Aguilar Fernández, Sergio; Mereu, Elisabetta; Moutinho, Cátia; Ruiz, Sara; Lorden, Patricia; Chin, Vanessa T.; Kaczorowski, Dominik; Chan, Chia-Ling; Gallagher, Richard; Chou, Angela; Planas Rigol, Ester; Rubio Perez, Carlota; Gut, Ivo G.; Piulats, Josep M.; Seoane, Joan; Powell, Joseph E.; Batlle, Eduard; Heyn, Holger
1-May-2014A symbiotic liaison between the genetic and epigenetic codeHeyn, Holger
1-Apr-2015Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation CarriersBlanco Guillermo, Ignacio; Cuadras, Daniel; Ruiz de Garibay, Gorka; Librado Sanz, Pablo; Sánchez-Gracia, Alejandro; Rozas Liras, Julio A.; Bonifaci Cano, Núria; Mateo González, Francesca; Berenguer, Antoni; Petit, Anna; Català, Isabel; Feliubadaló i Elorza, Maria Lídia; Tornero, Eva; Lázaro García, Conxi; Pujana Genestar, M. Ángel; Esteller, Manel; Gómez, Antonio; Sayols, Sergi; Vidal, Enrique; Heyn, Holger
28-Jun-2018bigSCale: an analytical framework for big-scale single-cell dataIacono, Giovanni; Mereu, Elisabetta; Guillaumet-Adkins, Amy; Corominas Castiñeira, Roser; Cuscó, Ivon; Rodríguez Esteban, Gustavo; Gut, Marta; Pérez-Jurado, Luis Alberto; Gut, Ivo; Heyn, Holger
24-Aug-2016Cancer network activity associated with therapeutic response and synergismSerra-Musach, Jordi; Mateo González, Francesca; Capdevila Busquets, Eva; Ruiz de Garibay, Gorka; Zhang, Xiaohu; Guha, Raj; Thomas, Craig J.; Grueso, Judit; Villanueva Garatachea, Alberto; Jaeger, Samira; Heyn, Holger; Vizoso, Miguel; Pérez-Montoyo, Hector; Cordero, Alex; González Suárez, Eva; Esteller, Manel; Moreno-Bueno, Gema; Tjärnberg, Andreas; Lázaro García, Conxi; Serra, Violeta; Arribas, Joaquín V. (Vicente); Benson, Mikael; Gustafsson, Mika; Ferrer, Marc; Aloy, Patrick, 1972-; Pujana Genestar, M. Ángel
7-Sep-2017Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumorsMartín Trujillo, Alex; Vidal, Enrique; Monteagudo Sánchez, Ana; Sánchez Delgado, Marta; Moran, Sebastian; Hernandez Mora, Jose Ramon; Heyn, Holger; Guitart, Miriam; Esteller, Manel; Monk, David
10-Nov-2021Dietary palmitic acid promotes a prometastatic memory via Schwann cellsPascual, Gloria; Dominguez, Diana; Elosúa Bayes, Marc; Beckedorff, Felipe; Laudanna, Carmelo; Bigas, Claudia; Douillet, Delphine; Greco, Carolina; Symeonidi, Aikaterini; Hernández, Inmaculada; Ruíz Gil, Sara; Prats, Neus; Bescós, Coro; Shiekhattar, Ramin; Amit, Moran; Heyn, Holger; Shilatifard, Ali; Aznar Benitah, Salvador
1-Dec-2013DNA methylation contributes to natural human variationHeyn, Holger; Moran, Sebastian; Hernando Herraez, Irene; Sayols, Sergi; Gomez, Antonio; Sandoval, Juan; Monk, Dave Nicholas; Hata, Kenichiro; Marques Bonet, Tomas; Wang, Liewei; Esteller, Manel
5-Oct-2015DNMT3A mutations mediate the epigenetic reactivation of the leukemogenic factor MEIS1 in acute myeloid leukemiaFerreira, Humberto J.; Heyn, Holger; Vizoso, Miguel; Moutinho, Cátia; Vidal, Enrique; Gomez, A; Martínez Cardús, Anna; Simó-Riudalbas, Laia; Moran, Sebastian; Jost, E; Esteller, Manel
Sep-2013Dynamics of DNA methylation in recent human and great ape evolutionHernando-Herraez, Irene; Prado-Martínez, Javier; Garg, Paras; Fernández-Callejo, Marcos; Heyn, Holger; Hvilsom, Christina; Navarro i Cuartiellas, Arcadi, 1969-; Esteller, Manel; Sharp, Andrew J.; Marquès i Bonet, Tomàs, 1975-
1-Jun-2015Epigenetic activation of a cryptic TBC1D16 transcript enhances melanoma progression by targeting EGFRVizoso, Miguel; Ferreira, Humberto J.; López Serra, Paula; Carmona, F. Javier; Martínez Cardús, Anna; Girotti, Maria Romina; Villanueva Garatachea, Alberto; Guil, Sonia; Moutinho, Cátia; Liz, Julia; Portela, Anna; Heyn, Holger; Moran, Sebastian; Vidal-Bel, August; Martínez Iniesta, María; Manzano, José Luis; Fernandez-Figueras, Maria Teresa; Élez, Elena; Muñoz-Couselo, Eva; Botella-Estrada, Rafael; Berrocal, Alfonso; Pontén, Fredrik; Oord, Joost van den; Gallagher, William M.; DenFrederick, Dennie T.; Flaherty, Keith T.; McDermott, Ultan; Lorigan, Paul; Marais, Richard; Esteller, Manel
24-Oct-2012Epigenetic Disruption of the Piwi Pathway in Human Spermatogenic DisordersHeyn, Holger; Ferreira, Humberto J.; Bassas, Lluís; Bonache, Sandra; Sayols, Sergi; Sandoval, Juan; Esteller, Manel; Larriba, Sara
2016Epigenetic inactivation of the putative DNA/RNA helicase SLFN11 in human cancer confers resistance to platinum drugsNogales, Vanesa; Reinhold, William C.; Varma, Sudhir; Martínez Cardús, Anna; Moutinho, Cátia; Moran, Sebastian; Heyn, Holger; Sebio, Ana; Barnadas i Molins, Agustí; Pommier, Yves; Esteller, Manel
26-Jan-2016Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancerHeyn, Holger; Vidal, Enrique; Ferreira, Humberto J.; Vizoso, Miguel; Sayols, Sergi; Gómez, Antonio; Moran, Sebastian; Boque-Sastre, Raquel; Guil, Sonia; Martínez Cardús, Anna; Lin, Charles Y.; Royo, Romina; Sanchez-Mut, Jose Vicente; Martínez, Ramón; Gut, Marta; Torrents Arenales, David; Orozco López, Modesto; Gut, Ivo G.; Young, Richard A.; Esteller, Manel
10-Sep-2019GATA2 Promotes Hematopoietic Development and Represses Cardiac Differentiation of Human MesodermCastaño, Julio; Aranda, Sergi; Bueno, Clara; Calero-Nieto, Fernando J.; Mejia-Ramirez, Eva; Mosquera Mayo, José Luís; Blanco, Enrique; Wang, Xiaonan; Prieto Rios, Cristina; Zabaleta, Lorea; Mereu, Elisabetta; Rovira, Meritxell; Jiménez-Delgado, Senda; Matson, Daniel R.; Heyn, Holger; Bresnick, Emery H.; Göttgens, Berthold; Di Croce, Luciano; Menéndez Buján, Pablo; Raya Chamorro, Ángel; Giorgetti, Alessandra
9-Aug-2013Global epigenomic reconfiguration during mammalian brain developmentLister, Ryan; Mukamel, Eran A.; Nery, Joseph R.; Urich, Mark; Puddifoot, Clare A.; Johnson, Nicholas D.; Lucero, Jacinta; Huang, Yun; Dwork, Andrew J.; Schultz, Matthew D.; Yu, Miao; Tonti Filippini, Julian; Heyn, Holger; Hu, Shijun; Wu, Joseph C.; Rao, Anjana; Esteller, Manel; He, Chuan; Haghighi, Fatemeh G; Sejnowski, Terrence J.; Behrens, M. Margarita; Ecker, Joseph R.
19-Jan-2016Human DNA methylomes of neurodegenerative diseases show common epigenomic patternsSanchez-Mut, Jose Vicente; Heyn, Holger; Vidal, Enrique; Moran, Sebastian; Sayols, Sergi; Delgado-Morales, Raul; Schultz, Matthew D.; Ansoleaga, Belén; Garcia Esparcia, Paula; Pons-Espinal, Meritxell; Lagran, M. M. de; Dopazo, Joaquín; Rabano, Alberto; Avila, Jesús; Dierssen, Mara; Lott, I.; Ferrer, Isidro (Ferrer Abizanda); Ecker, Joseph R.; Esteller, Manel