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Title: Iron oxide nanoparticles for magnetically guided and magnetically responsive drug delivery
Author: Estelrich i Latràs, Joan
Escribano Ferrer, Elvira
Queralt i Regué, Josep
Busquets i Viñas, Ma. Antonia
Keywords: Nanopartícules
Òxid de ferro
Ferric oxide
Issue Date: 10-Apr-2015
Publisher: MDPI
Abstract: In this review, we discuss the recent advances in and problems with the use of magnetically-guided and magnetically-responsive nanoparticles in drug delivery and magnetofection. In magnetically-guided nanoparticles, a constant external magnetic field is used to transport magnetic nanoparticles loaded with drugs to a specific site within the body or to increase the transfection capacity. Magnetofection is the delivery of nucleic acids under the influence of a magnetic field acting on nucleic acid vectors that are associated with magnetic nanoparticles. In magnetically-responsive nanoparticles, magnetic nanoparticles are encapsulated or embedded in a larger colloidal structure that carries a drug. In this last case, an alternating magnetic field can modify the structure of the colloid, thereby providing spatial and temporal control over drug release.
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It is part of: International Journal of Molecular Sciences, 2015, vol. 16, num. 4, p. 8070-8101
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ISSN: 1661-6596
Appears in Collections:Articles publicats en revistes (Farmàcia, Tecnologia Farmacèutica i Fisicoquímica)
Articles publicats en revistes (Bioquímica i Fisiologia)
Articles publicats en revistes (Institut de Nanociència i Nanotecnologia (IN2UB))

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