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Title: The effect of maternal obesity on breast milk fatty acids and its association with infant growth and cognition-The Preobe follow-up
Author: Garza Puentes, Andrea de la
Martí Alemany, Adrià
Chisaguano Tonato, Aida Maribel
Montes Goyanes, Rosa
Castellote Bargalló, Ana Isabel
Torres Espinola, Francisco José
García-Valdés, Luz
Escudero-Marín, Mireia
Segura Moreno, Maite
Campoy, Cristina
López Sabater, María del Carmen
Keywords: Llet materna
Àcids grassos omega-3
Desenvolupament infantil
Breast milk
Omega-3 fatty acids
Child development
Issue Date: 9-Sep-2019
Publisher: MDPI
Abstract: This study analyzed how maternal obesity a ected fatty acids (FAs) in breast milk and their association with infant growth and cognition to raise awareness about the programming e ect of maternal health and to promote a healthy prenatal weight. Mother-child pairs (n = 78) were grouped per maternal pre-pregnancy body mass index (BMI): normal-weight (BMI = 18.5-24.99), overweight (BMI = 25-29.99) and obese (BMI > 30). Colostrum and mature milk FAs were determined. Infant anthropometry at 6, 18 and 36 months of age and cognition at 18 were analyzed. Mature milk exhibited lower arachidonic acid (AA) and docosahexaenoic acid (DHA), among others, than colostrum. Breast milk of non-normal weight mothers presented increased saturated FAs and n6:n3 ratio and decreased -linolenic acid (ALA), DHA and monounsaturated FAs. Infant BMI-for-age at 6 months of age was inversely associated with colostrum n6 (e.g., AA) and n3 (e.g., DHA) FAs and positively associated with n6:n3 ratio. Depending on the maternal weight, infant cognition was positively influenced by breast milk linoleic acid, n6 PUFAs, ALA, DHA and n3 LC-PUFAs, and negatively a ected by n6:n3 ratio. In conclusion, this study shows that maternal pre-pregnancy BMI can influence breast milk FAs and infant growth and cognition, endorsing the importance of a healthy weight in future generations.
Note: Reproducció del document publicat a:
It is part of: Nutrients, 2019, vol. 11, num. 9, p. 2154
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ISSN: 2072-6643
Appears in Collections:Articles publicats en revistes (Institut de Recerca en Nutrició i Seguretat Alimentària (INSA·UB))
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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