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http://hdl.handle.net/2445/101981
Title: | Highly Enantioselective Iridium-Catalyzed Hydrogenation of Cyclic Enamides |
Author: | Salomó i Prat, Ernest Orgué Gassol, Sílvia Riera i Escalé, Antoni Verdaguer i Espaulella, Xavier |
Keywords: | Hidrogenació Catàlisi asimètrica Enantiòmers Hydrogenation Enantioselective catalysis Enantiomers |
Issue Date: | 17-May-2016 |
Publisher: | Wiley |
Abstract: | The MaxPHOX-Ir catalyst system provided the highest selectivity ever reported for the redn. of cyclic enamides derived from α- and β-tetralones. This result indicates that iridium catalysts are also proficient in reducing alkenes bearing metal-coordinating groups. In the present system, selectivity was pressure-dependent: in most cases, a decrease in the H2 pressure to 3 bar resulted in an increase in enantioselectivity. Moreover, the process can be carried out in environmentally friendly solvents, such as methanol and Et acetate, with no loss of selectivity. |
Note: | Reproducció del document publicat a: http://dx.doi.org/10.1002/anie.201602219 |
It is part of: | Angewandte Chemie International Edition, 2016, vol. 55, p. 7988-7992 |
URI: | http://hdl.handle.net/2445/101981 |
Related resource: | http://dx.doi.org/10.1002/anie.201602219 |
ISSN: | 0003-3022 |
Appears in Collections: | Articles publicats en revistes (Química Inorgànica i Orgànica) Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona)) |
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