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http://hdl.handle.net/2445/107269
Title: | Self-perceived quality of life among patients with Alzheimer's disease: Two longitudinal models of analysis |
Author: | Conde Sala, Josep Lluís Turró-Garriga, Oriol Portellano Ortiz, Cristina Viñas-Diez, Vanesa Gascón-Bayarri, Jordi Reñé Ramírez, Ramon |
Keywords: | Malaltia d'Alzheimer Satisfacció dels pacients Mètode longitudinal Alzheimer's disease Patient satisfaction Longitudinal method |
Issue Date: | 22-Feb-2016 |
Publisher: | IOS Press |
Abstract: | The objective was to analyze the factors that influence self-perceived quality of life (QoL) in patients with Alzheimer's disease (AD), contrasting two different longitudinal models. A total of 127 patients were followed up over 24 months. The instruments applied were: Quality of Life in Alzheimer's Disease scale (QoL-AD), Geriatric Depression Scale-15, Anosognosia Questionnaire-Dementia, Disability Assessment in Dementia, Neuropsychiatric Inventory, and the Mini Mental State Examination. Two models for grouping patients were tested: 1) Baseline score on the QoL-AD (QoL-Baseline), and 2) Difference in QoL-AD score between baseline and follow-up (QoL-Change). Generalized estimating equations (GEE) were used to analyze longitudinal data, and multinomial regression analyses were performed. Over the follow-up period the QoL-Baseline model showed greater variability between groups (Wald χ2 = 172.3, p < 0.001) than did the QoL-Change model (Wald χ2 = 1.7, p = 0.427). In the QoL-Baseline model the predictive factors were greater depression (odds ratio [OR] = 1.20; 95% CI: 1.00-1.45) and lower functional ability (OR = 0.92; 95% CI: 0.85-0.99) for the Low QoL group (< 33 QoL-AD), and less depression (OR = 0.68; 95% CI: 0.52-0.88), more anosognosia (OR = 1.07; 95% CI: 1.01-1.13), and fewer neuropsychiatric symptoms (OR = 0.95; 95% CI: 0.91-0.99) for the High-QoL group (>37 QoL-AD). The model based on baseline scores (QoL-Baseline) was better than the QoL-Change model in terms of identifying trajectories and predictors of QoL in AD. |
Note: | Reproducció del document publicat a: https://doi.org/10.3233/JAD-160040 |
It is part of: | Journal of Alzheimer's Disease, 2016, vol. 52, num. 3, p. 999-1012 |
URI: | http://hdl.handle.net/2445/107269 |
Related resource: | https://doi.org/10.3233/JAD-160040 |
ISSN: | 1387-2877 |
Appears in Collections: | Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
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