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http://hdl.handle.net/2445/156959| Title: | The role of platelet-activating factor antagonists in the prohylasis of postransplant acute tubular necrosis |
| Author: | Grinyó Boira, Josep M. Torras Ambròs, Joan Valles, Joaquim |
| Keywords: | Trasplantament renal Necrosi Agregació plaquetària Kidney transplantation Necrosis Blood platelet aggregation |
| Issue Date: | 1-May-1996 |
| Publisher: | Marcel Dekker |
| Abstract: | Renal reperfusion injury can be defined as the renal damage suffered by a kidney because of reestablishment of blood flow prolonged ischemia. Increased permeability for calcium ions, subsequent activation of endogenous phospholipases, and damage mediated by oxygen free radicals are involved in this reperfusion injury. Inhibition of inflammatory mediators of endothelial origin, such as superoxide radicals and platelet-activating factor (PAF), is a possible way of protecting the injured endothelium following blood reperfusion. |
| Note: | Reproducció del document publicat a: https://doi.org/10.3109/08860229609052815 |
| It is part of: | Renal Failure, 1996, vol. 18, num. 3, p. 445-451 |
| URI: | http://hdl.handle.net/2445/156959 |
| Related resource: | https://doi.org/10.3109/08860229609052815 |
| ISSN: | 0886-022X |
| Appears in Collections: | Articles publicats en revistes (Ciències Clíniques) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 125193.pdf | 3.94 MB | Adobe PDF | View/Open |
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