Please use this identifier to cite or link to this item:
http://hdl.handle.net/2445/157650
Title: | Nomograms of Fetal Cardiac Dimensions at 18-41 Weeks of Gestation |
Author: | García Otero, Laura Gómez, Olga Rodríguez López, Mérida Torres, Ximena Soveral, Iris Sepúlveda Martínez, Álvaro Guirado, Laura Valenzuela Alcaraz, Brenda I. López, Marta Martínez Crespo, Josep M. (Josep Maria) Gratacós Solsona, Eduard Crispi Brillas, Fàtima |
Keywords: | Medicina prenatal Medicina intensiva en cardiologia Prenatal medicine Cardiac intensive care |
Issue Date: | 4-Jan-2019 |
Publisher: | Karger |
Abstract: | OBJECTIVE: There is a need for standardized reference values for cardiac dimensions in prenatal life. The objective of the present study was to construct nomograms for fetal cardiac dimensions using a well-defined echocardiographic methodology in a low-risk population. METHODS: This is a prospective cohort study including 602 low-risk singleton pregnancies undergoing a standardized fetal echocardiography to accurately assess fetal cardiac, ventricular, and atrial dimensions. Parametric regressions were tested to model each measurement against gestational age from 18 to 41 weeks of gestation. RESULTS: Nomograms were constructed for fetal cardiac dimensions (transverse and longitudinal diameters and areas) of the whole heart, atria, and ventricles, as well as myocardial wall thicknesses. All dimensions showed a progressive increase with gestational age. The best model for most parameters was a second-degree linear polynomial. Fetal cardiac, ventricular, and atrial diameters and areas were successfully obtained in 98.6% of the fetuses, while myocardial wall thicknesses could be obtained in 96.5% of the population. The results showed excellent interobserver and intraobserver reproducibility (intraclass correlation coefficient, ICC > 0.811 and ICC > 0.957, respectively). CONCLUSIONS: We provide standardized and comprehensively evaluated reference values for fetal cardiac morphometric parameters across gestation in a low-risk population. These no mograms would enable the early identification of different patterns of fetal cardiac remodeling. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1159/000494838 |
It is part of: | Fetal Diagnosis and Therapy, 2019, vol. 47, num. 5 |
URI: | http://hdl.handle.net/2445/157650 |
Related resource: | https://doi.org/10.1159/000494838 |
ISSN: | 1015-3837 |
Appears in Collections: | Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques) Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer) Articles publicats en revistes (BCNatal Fetal Medicine Research Center) |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
690436.pdf | 1.34 MB | Adobe PDF | View/Open |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.