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http://hdl.handle.net/2445/167458
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DC Field | Value | Language |
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dc.contributor.author | Rabassa Bonet, Montserrat | - |
dc.contributor.author | Zamora-Ros, Raul | - |
dc.contributor.author | Palau Rodríguez, Magalí | - |
dc.contributor.author | Tulipani, Sara | - |
dc.contributor.author | Miñarro Alonso, Antonio | - |
dc.contributor.author | Bandinelli, Stefania | - |
dc.contributor.author | Ferrucci, Luigi | - |
dc.contributor.author | Cherubini, Antonio | - |
dc.contributor.author | Andrés Lacueva, Ma. Cristina | - |
dc.date.accessioned | 2020-07-03T08:10:18Z | - |
dc.date.available | 2021-01-07T06:10:21Z | - |
dc.date.issued | 2020-01-07 | - |
dc.identifier.issn | 1613-4125 | - |
dc.identifier.uri | http://hdl.handle.net/2445/167458 | - |
dc.description.abstract | Scope: The association between self-reported dietary intake and urinary metabolomic markers of habitual nut exposure with cognitive decline over a 3-year follow-up in an older Italian population is prospectively evaluated. Methods and results: A total of 119 older participants are selected, based on self-referred nut intake: the non-nut consumer (n = 72) and the regular consumer (≥2.9 g d-1 , n = 47). Nut exposure is measured at baseline either with the use of a validated food frequency questionnaire or with an HPLC-Q-ToF-MS metabolomic approach. Three years after, 28 from the nonconsumers and 10 from the consumers experienced cognitive decline. Dietary nut exposure is characterized by urinary metabolites of polyphenols and fatty acids pathways. Nut consumption estimated either by the dietary marker or by the urinary marker model is in both cases associated with less cognitive decline (OR: 0.78, 95% CI: 0.61,0.99; p = 0.043 and OR: 0.995, 95% CI: 0.991,0.999; p = 0.016, respectively) with AUCs 73.2 (95% CI: 62.9, 83.6) and 73.1 (62.5, 83.7), respectively. Conclusions: A high intake of nuts may protect older adults from cognitive decline. Metabolomics provides accurate and complementary information of the nut exposure and reinforces the results obtained using dietary information. | - |
dc.format.extent | 11 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | spa | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1002/mnfr.201900532 | - |
dc.relation.ispartof | Molecular Nutrition & Food Research, 2020, vol. 64, num. 2, p. e1900532 | - |
dc.relation.uri | https://doi.org/10.1002/mnfr.201900532 | - |
dc.rights | (c) Wiley-VCH, 2020 | - |
dc.source | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) | - |
dc.subject.classification | Cuina (Nous) | - |
dc.subject.classification | Cognició | - |
dc.subject.classification | Envelliment | - |
dc.subject.classification | Metabolòmica | - |
dc.subject.classification | Dietètica | - |
dc.subject.classification | Salut | - |
dc.subject.other | Cooking (Nuts) | - |
dc.subject.other | Cognition | - |
dc.subject.other | Aging | - |
dc.subject.other | Metabolomics | - |
dc.subject.other | Dietetics | - |
dc.subject.other | Health | - |
dc.title | Habitual Nut Exposure, Assessed by Dietary and Multiple Urinary Metabolomic Markers, and Cognitive Decline in Older Adults: The InCHIANTI Study. | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/acceptedVersion | - |
dc.identifier.idgrec | 694887 | - |
dc.date.updated | 2020-07-03T08:10:18Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 31755209 | - |
Appears in Collections: | Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia) Articles publicats en revistes (Institut de Recerca en Nutrició i Seguretat Alimentària (INSA·UB)) Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL)) |
Files in This Item:
File | Description | Size | Format | |
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694887.pdf | 272.56 kB | Adobe PDF | View/Open |
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