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Title: Lipids and physical function in older adults
Author: Casas Agustench, Patricia
Cherubini, Antonio
Andrés-Lacueva, C.
Keywords: Lípids en la nutrició
Persones grans
Lipids in human nutrition
Older people
Issue Date: 7-Oct-2016
Publisher: Lippincott, Williams & Wilkins. Wolters Kluwer Health
Abstract: PURPOSE OF REVIEW: Healthy aging is a public health priority. The maintenance of adequate physical function is recognized as a key element of healthy aging. In recent years, scientific evidence has increased concerning the ability of lipids, in particular omega 3 polyunsaturated fatty acids (n-3 PUFAs), to positively influence muscle and overall physical function in older patients. The article will critically review observational as well as intervention studies on this topic, and it will elucidate the potential biological mechanisms underlying the beneficial effects of n-3 PUFA on physical function. RECENT FINDINGS: Observational studies and clinical trials performed in healthy older patients and in older patients with chronic diseases mostly found positive effects of n-3 PUFA on muscle metabolism, muscle strength and in general physical function. SUMMARY: Although the use of n-3 PUFA might represent an important intervention to preserve physical function in older adults, several key questions still need to be answered. Above all, large randomized controlled trials should be performed to confirm the utility of n-3 PUFA as therapeutic agents to prevent and treat physical function decline in old age.
Note: Versió postprint del document publicat a:
It is part of: Current Opinion in Clinical Nutrition and Metabolic Care, 2016, vol. 20, num. 1, p. 16-25
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ISSN: 1363-1950
Appears in Collections:Articles publicats en revistes (Institut de Recerca en Nutrició i Seguretat Alimentària (INSA·UB))
Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)

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