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Title: Quantifying forces in cell biology
Author: Roca-Cusachs Soulere, Pere
Conte, Vito
Trepat Guixer, Xavier
Keywords: Cèl·lules
Membranes cel·lulars
Propietats mecàniques
Cell membranes
Mechanical properties
Issue Date: 1-Jul-2017
Publisher: Nature Publishing Group
Abstract: Cells exert, sense, and respond to physical forces through an astounding diversity of mechanisms. Here we review recently developed tools to quantify the forces generated by cells. We first review technologies based on sensors of known or assumed mechanical properties, and discuss their applicability and limitations. We then proceed to draw an analogy between these human-made sensors and force sensing in the cell. As mechanics is increasingly revealed to play a fundamental role in cell function we envisage that tools to quantify physical forces may soon become widely applied in life-sciences laboratories.
Note: Versió postprint del document publicat a:
It is part of: Nature Cell Biology, 2017, vol. 19, num. 7, p. 742-751
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ISSN: 1465-7392
Appears in Collections:Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))
Publicacions de projectes de recerca finançats per la UE
Articles publicats en revistes (Biomedicina)

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