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Title: Proresolving lipid mediators and liver disease.
Author: Clària i Enrich, Joan
Flores Costa, Roger
Duran Güell, Marta
López Vicario, Cristina
Keywords: Malalties del fetge
Liver diseases
Issue Date: Nov-2021
Publisher: Elsevier B.V.
Abstract: Inflammation is a characteristic feature of virtually all acute and chronic liver diseases. It intersects different liver pathologies from the early stages of liver injury, when the inflammatory burden is mild-to-moderate, to very advanced stages of liver disease, when the inflammatory response is very intense and drives multiple organ dysfunction and failure(s). The current review describes the most relevant features of the inflammatory process in two different clinical entities across the liver disease spectrum, namely non-alcoholic steatohepatitis (NASH) and acute-on-chronic liver failure (ACLF). Special emphasis is given within these two disease conditions to gather the most relevant data on the specialized pro-resolving mediators that orchestrate the resolution of inflammation, a tightly controlled process which dysregulation commonly associates with chronic inflammatory conditions.
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It is part of: Biochimica et Biophysica Acta-Molecular and Cell Biology of Lipids, 2021, vol. 1866, num. 11, p. 159023
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ISSN: 1388-1981
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Biomedicina)

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