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http://hdl.handle.net/2445/185257
Title: | COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring |
Author: | Ayesa-Arriola, Rosa López-Díaz, Álvaro Ruiz-Veguilla, Miguel Leza, Juan Carlos Fañanás Saura, Lourdes Crespo-Facorro, Benedicto |
Keywords: | COVID-19 Malalties mentals COVID-19 Mental illness |
Issue Date: | Jan-2021 |
Publisher: | Elsevier España |
Abstract: | Study of the effects of prenatal maternal infection on early offspring brain development has long attracted the interest and endeavors of clinicians and neuroscientists.1 Early reports on large-scale ecological data and further birth cohort studies analyzing biomarkers in pregnancy and early life of offspring have yielded evidence that in-utero exposure to infection increases neuropsychiatric disorder risk, particularly schizophrenia and autism spectrum disorders.2, 3, 4 The main hypothesis derived from these studies is that activation of immune-inflammatory pathways during maternal infection may result in abnormal fetal brain development.5 However, such a hypothesis requires detailed testing to reveal the pathogenic and pathophysiological mechanisms behind these neurodevelopmental alterations. |
Note: | Versió postprint del document publicat a: https://doi.org/10.1016/j.rpsm.2020.12.003 |
It is part of: | Revista de Psiquiatria y Salud Mental, 2021, vol. 14, num. 1, p. 1-3 |
URI: | http://hdl.handle.net/2445/185257 |
Related resource: | https://doi.org/10.1016/j.rpsm.2020.12.003 |
ISSN: | 1888-9891 |
Appears in Collections: | Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals) |
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