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cc-by-nc-nd (c) Sociedad Española de Psiquiatría y Sociedad Española de Psiquiatría Biológica, 2021
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/185257

COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring

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Study of the effects of prenatal maternal infection on early offspring brain development has long attracted the interest and endeavors of clinicians and neuroscientists.1 Early reports on large-scale ecological data and further birth cohort studies analyzing biomarkers in pregnancy and early life of offspring have yielded evidence that in-utero exposure to infection increases neuropsychiatric disorder risk, particularly schizophrenia and autism spectrum disorders.2, 3, 4 The main hypothesis derived from these studies is that activation of immune-inflammatory pathways during maternal infection may result in abnormal fetal brain development.5 However, such a hypothesis requires detailed testing to reveal the pathogenic and pathophysiological mechanisms behind these neurodevelopmental alterations.

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AYESA-ARRIOLA, Rosa, et al. COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring. Revista de Psiquiatria y Salud Mental. 2021. Vol. 14, num. 1, pags. 1-3. ISSN 1888-9891. [consulted: 23 of May of 2026]. Available at: https://hdl.handle.net/2445/185257

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