Please use this identifier to cite or link to this item:
Title: Microwave-Based Colonoscopy: Preclinical Evaluation in an Ex Vivo Human Colon Model
Author: Fernández Esparrach, Glòria
Garrido, Alejandra
Sont, Roberto
Dghoughi, Walid
Marcoval, Sergi
Cuatrecasas Freixas, Miriam
López-Prades, Sandra
De Lacy, F. Borja
Pellisé Urquiza, Maria
Belda, Ignasi
Guardiola, Marta
Keywords: Colonoscòpia
Dispositius de microones
Cirurgia colorectal
Pòlips (Patologia)
Microwave devices
Colorectal surgery
Polyps (Pathology)
Issue Date: 28-Jan-2022
Publisher: Hindawi
Abstract: Introduction: Microwave imaging can obtain 360° anatomical and functional images of the colon representing the existing contrast in dielectric properties between different tissues. Microwaves are safe (nonionizing) and have the potential of reducing the visualization problems of conventional colonoscopy. This study assessed the efficacy of a microwave-based colonoscopy device to detect neoplastic lesions in an ex vivo human colon model. Methods: Fresh surgically excised colorectal specimens containing cancer or polyps were fixed to a 3D positioning system, and the accessory device was introduced horizontally inside the ex vivo colon lumen and moved along it simulating a real colonoscopy exploration. Measurements of the colon were taken every 4 mm with the microwave-based colonoscopy device and processed with a microwave imaging algorithm. Results: 14 ex vivo human colorectal specimens with carcinomas (n = 11) or adenomas with high grade dysplasia (n = 3) were examined with a microwave-based device. Using a detection threshold of 2.79 for the dielectric property contrast, all lesions were detected without false positives or false negatives. Conclusions: This study demonstrates the use of a microwave-based device to be used as an accessory of a standard colonoscope to detect neoplastic lesions in surgically excised colorectal specimens.
Note: Reproducció del document publicat a:
It is part of: Gastroenterology Research and Practice, 2022, vol. 2022, p. 9522737
Related resource:
ISSN: 1687-6121
Appears in Collections:Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)
Articles publicats en revistes (Fonaments Clínics)

Files in This Item:
File Description SizeFormat 
729696.pdf957.66 kBAdobe PDFView/Open

This item is licensed under a Creative Commons License Creative Commons