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DC Field | Value | Language |
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dc.contributor.author | Riba, Jordi | - |
dc.contributor.author | Rodríguez Fornells, Antoni | - |
dc.contributor.author | Morte, Adelaida | - |
dc.contributor.author | Münte, Thomas F. | - |
dc.contributor.author | Barbanoj, Manel J. | - |
dc.date.accessioned | 2015-04-28T17:25:07Z | - |
dc.date.available | 2015-04-28T17:25:07Z | - |
dc.date.issued | 2005 | - |
dc.identifier.issn | 0270-6474 | - |
dc.identifier.uri | http://hdl.handle.net/2445/65265 | - |
dc.description.abstract | Noradrenergic neurotransmission has been associated with the modulation of higher cognitive functions mediated by the prefrontal cortex. In the present study, the impact of noradrenergic stimulation on the human action-monitoring system, as indexed by eventrelated brain potentials, was examined. After the administration of a placebo or the selective 2 -adrenoceptor antagonist yohimbine, which stimulates firing in the locus ceruleus and noradrenaline release, electroencephalograpic recordings were obtained from healthy volunteers performing a letter flanker task. Yohimbine led to an increase in the amplitude of the error-related negativity in conjunction with a significant reduction of action errors. Reaction times were unchanged, and the drug did not modify the N2 in congruent versus incongruent trials, a measure of preresponse conflict, or posterror adjustments as measured by posterror slowing of reaction time. The present findings suggest that the locus ceruleus<br>noradrenaline system exerts a rather specific effect on human action monitoring. | - |
dc.format.extent | 5 p. | - |
dc.format.mimetype | application/pdf | - |
dc.language.iso | eng | - |
dc.publisher | The Society for Neuroscience | - |
dc.relation.isformatof | Reproducció del document publicat a: http://dx.doi.org/10.1523/JNEUROSCI.4437-04.2005 | - |
dc.relation.ispartof | Journal of Neuroscience, 2005, vol. 25, num. 17, p. 4370-4374 | - |
dc.relation.uri | http://dx.doi.org/10.1523/JNEUROSCI.4437-04.2005 | - |
dc.rights | cc-by-nc-sa (c) Riba, J. et al., 2005 | - |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/3.0/es | - |
dc.source | Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) | - |
dc.subject.classification | Potencials evocats (Electrofisiologia) | - |
dc.subject.classification | Escorça cerebral | - |
dc.subject.classification | Catecolamines | - |
dc.subject.classification | Conducta (Psicologia) | - |
dc.subject.other | Evoked potentials (Electrophysiology) | - |
dc.subject.other | Cerebral cortex | - |
dc.subject.other | Catecholamines | - |
dc.subject.other | Human behavior | - |
dc.title | Noradrenergic stimulation enhances human action monitoring | - |
dc.type | info:eu-repo/semantics/article | - |
dc.type | info:eu-repo/semantics/publishedVersion | - |
dc.identifier.idgrec | 522139 | - |
dc.date.updated | 2015-04-28T17:25:08Z | - |
dc.rights.accessRights | info:eu-repo/semantics/openAccess | - |
dc.identifier.pmid | 15858063 | - |
Appears in Collections: | Articles publicats en revistes (Cognició, Desenvolupament i Psicologia de l'Educació) |
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File | Description | Size | Format | |
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522139.pdf | 227.55 kB | Adobe PDF | View/Open |
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