In vivo verification of treatment source dwell times in brachytherapy of postoperative endometrial carcinoma: a feasibility study

dc.contributor.authorHerreros, Antonio
dc.contributor.authorPérez Calatayud, José
dc.contributor.authorBallester, Facundo
dc.contributor.authorBarrera Gómez, José
dc.contributor.authorAbellana Sangrà, Rosa Mari
dc.contributor.authorMelo, Joana
dc.contributor.authorMoutinho, Luis
dc.contributor.authorTagliaferri, L.
dc.contributor.authorRovirosa Casino, Angeles
dc.date.accessioned2023-02-13T13:25:16Z
dc.date.available2023-02-13T13:25:16Z
dc.date.issued2022-05-31
dc.date.updated2023-02-13T13:25:16Z
dc.description.abstractBackground: In brachytherapy, there are still many manual procedures that can cause adverse events which can be detected with in vivo dosimetry systems. Plastic scintillator dosimeters (PSD) have interesting properties to achieve this objective such as real-time reading, linearity, repeatability, and small size to fit inside brachytherapy catheters. The purpose of this study was to evaluate the performance of a PSD in postoperative endometrial brachytherapy in terms of source dwell time accuracy. Methods: Measurements were carried out in a PMMA phantom to characterise the PSD. Patient measurements in 121 dwell positions were analysed to obtain the differences between planned and measured dwell times. Results: The repeatability test showed a relative standard deviation below 1% for the measured dwell times. The relative standard deviation of the PSD sensitivity with accumulated absorbed dose was lower than 1.2%. The equipment operated linearly in total counts with respect to absorbed dose and also in count rate versus absorbed dose rate. The mean (standard deviation) of the absolute differences between planned and measured dwell times in patient treatments was 0.0 (0.2) seconds. Conclusions: The PSD system is useful as a quality assurance tool for brachytherapy treatments.
dc.format.extent13 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec723843
dc.identifier.issn2075-4426
dc.identifier.pmid35743696
dc.identifier.urihttps://hdl.handle.net/2445/193520
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/jpm12060911
dc.relation.ispartofJournal of Personalized Medicine, 2022, vol. 12, num. 6
dc.relation.urihttps://doi.org/10.3390/jpm12060911
dc.rightscc-by (c) Herreros, Antonio et al., 2022
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Fonaments Clínics)
dc.subject.classificationCàncer d'endometri
dc.subject.classificationBraquiteràpia
dc.subject.classificationCura postoperatòria
dc.subject.classificationCàncer ginecològic
dc.subject.classificationEstudis de viabilitat
dc.subject.otherEndometrial cancer
dc.subject.otherRadioisotope brachytherapy
dc.subject.otherPostoperative care
dc.subject.otherGynecologic cancer
dc.subject.otherFeasibility studies
dc.titleIn vivo verification of treatment source dwell times in brachytherapy of postoperative endometrial carcinoma: a feasibility study
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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