Orthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoles

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dc.contributor.authorRuiz Sanchis, Pau
dc.contributor.authorSavina, Svetlana A.
dc.contributor.authorAcosta, Gerardo A.
dc.contributor.authorAlbericio Palomera, Fernando
dc.contributor.authorÁlvarez Domingo, Mercedes
dc.date.accessioned2014-06-02T08:10:38Z
dc.date.available2021-11-01T06:10:14Z
dc.date.issued2011-11-22
dc.date.updated2014-05-30T11:35:20Z
dc.description.abstractThe synthesis of various polycyclic systems containing a C3a-Ni bond between a hexahydropyrrolo[2,3-b]indole and an indole tryptophan is described here. A series of experiments were performed to determine the best combination of five orthogonal protecting groups and the best reaction conditions for formation of said bond, which is a common feature among many recently discovered marine natural products.
dc.format.extent7 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec598515
dc.identifier.issn1434-193X
dc.identifier.urihttps://hdl.handle.net/2445/54707
dc.language.isoeng
dc.publisherWiley-VCH
dc.relation.isformatofVersió preprint del document publicat a: http://dx.doi.org/10.1002/ejoc.201101057
dc.relation.ispartofEuropean Journal of Organic Chemistry, 2012, vol. 2012, num. 1, p. 67-73
dc.relation.urihttp://dx.doi.org/10.1002/ejoc.201101057
dc.rights(c) Wiley-VCH Verlag GmbH & Co. KGaA, 2012
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationProductes naturals marins
dc.subject.classificationQuímica heterocíclica
dc.subject.classificationAminoàcids
dc.subject.classificationSíntesi de pèptids
dc.subject.otherMarine natural products
dc.subject.otherHeterocyclic chemistry
dc.subject.otherAmino acids
dc.subject.otherPeptide synthesis
dc.titleOrthogonal protecting groups in the synthesis of tryptophanyl-hexahydropyrroloindoleseng
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/submittedVersion

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