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cc by-nc-nd (c) Migliori et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/154277

MDR/XDR-TB management of patients and contacts: challenges facing the new decade. The 2020 clinical update by the Global Tuberculosis Network

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The continuous flow of new research articles on MDR-TB diagnosis, treatment, prevention and rehabilitation requires frequent update of existing guidelines. This review is aimed at providing clinicians and public health staff with an updated and easy-to-consult document arising from consensus of Global Tuberculosis Network (GTN) experts. The core published documents and guidelines have been reviewed including the recently published MDR-TB WHO rapid advice and ATS/CDC/ERS/IDSA guidelines. After a rapid review of epidemiology and risk factors, the clinical priorities on MDR-TB diagnosis (including whole genome sequencing and drug-susceptibility testing interpretations) and treatment (treatment design and management, TB in children) are discussed. Furthermore, the review comprehensively describes the latest information on contact tracing and LTBI management in MDR-TB contacts, while providing guidance on post-treatment functional evaluation and rehabilitation of TB sequelae, infection control and other public health priorities.

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MIGLIORI, Giovanni battista, TIBERI, Simon, ZUMLA, Alimuddin, PETERSEN, Eskild, MUHWA CHAKAYA, Jeremiah, WEJSE, Christian, MUÑOZ TORRICO, Marcela, DUARTE, Raquel, ALFFENAAR, Jan-willem, SCHAAF, H. simon, MARAIS, Ben j., CIRILLO, Daniela maria, ALAGNA, Riccardo, RENDON, Adrian, PONTALI, Emanuele, PIUBELLO, Alberto, FIGUEROA, José, FERLAZZO, Gabriella, GARCÍA-BASTEIRO, Alberto l., CENTIS, Rosella, VISCA, Dina, AMBROSIO, Lia d’, SOTGIU, Giovanni, Global Tuberculosis Network. MDR/XDR-TB management of patients and contacts: challenges
                facing the new decade. The 2020 clinical update by the Global
                Tuberculosis Network. _International Journal of Infectious Diseases_. 2020. Vol. 92, núm. S15-S25. [consulta: 21 de gener de 2026]. ISSN: 1201-9712. [Disponible a: https://hdl.handle.net/2445/154277]

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