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cc by (c) Demeter, Katalin et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/201625

Have genetic targets for faecal pollution diagnostics and source tracking revolutionised water quality analysis yet?

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The impacts on faecal pollution analysis using nucleic acid-based methods, such as PCR and sequencing, in health-related water quality research were assessed by rigorous literature analysis. A wide range of application areas and study designs has been identified since the first application more than 30 years ago (>1,100 publications). Given the consistency of methods and assessment types, we suggest defining this emerging part of science as a new discipline: genetic faecal pollution diagnostics (GFPD) in health-related microbial water quality analysis. Undoubtedly, GFPD has already revolutionised faecal pollution detection and microbial source tracking, the current core applications. GFPD is also expanding to many other research areas, including infection and health risk assessment, evaluation of microbial water treatment, and support of wastewater surveillance. In addition, storage of DNA extracts allows for biobanking, which opens up new perspectives. The tools of GFPD can be combined with cultivation-based standardised faecal indicator enumeration, pathogen detection, and various environmental data types, in an integrated data analysis approach. This comprehensive meta-analysis provides the scientific status quo of this field, including trend analyses and literature statistics, outlining identified application areas, and discussing the benefits and challenges of nucleic acid-based analysis in GFPD.

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DEMETER, Katalin, LINKE, Rita, BALLESTÉ PAU, Elisenda, REISCHER, Georg, MAYER, René e., VIERHEILIG, Julia, KOLM, Claudia, STEVENSON, Margaret e., DERX, Julia, KIRSCHNER, Alexander k.t., SOMMER, Regina, SHANKS, Orin c., BLANCH I GISBERT, Anicet, ROSE, Joan b., AHMED, Warish, FARNLEITNER, Andreas h.. Have genetic targets for faecal pollution diagnostics and source tracking revolutionised water quality analysis yet?. _FEMS Microbiology Reviews_. 2023. Vol. 47, núm. 4, pàgs. 1-36. [consulta: 25 de febrer de 2026]. ISSN: 0168-6445. [Disponible a: https://hdl.handle.net/2445/201625]

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