A practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines

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dc.contributor.authorAmat Tusón, Mercedes
dc.contributor.authorNavío, Laura
dc.contributor.authorLlor Brunés, Núria
dc.contributor.authorMolins, Elies
dc.contributor.authorBosch Cartes, Joan
dc.date.accessioned2020-06-03T09:40:22Z
dc.date.available2020-06-03T09:40:22Z
dc.date.issued2012-01-06
dc.date.updated2020-06-03T09:40:22Z
dc.description.abstractStarting from 4-substituted cyclohexanones, a practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines has been developed, the key steps being a stereoselective cyclocondensation of an unsaturated δ-keto ester derivative with (R)-phenylglycinol and the stereoselective hydrogenation of the resulting tricyclic oxazoloquinolone lactams.
dc.format.extent4 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec603300
dc.identifier.issn1523-7060
dc.identifier.pmid22133083
dc.identifier.urihttps://hdl.handle.net/2445/164139
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1021/ol2030058
dc.relation.ispartofOrganic Letters, 2012, vol. 14, num. 1, p. 210-213
dc.relation.urihttps://doi.org/10.1021/ol2030058
dc.rights(c) American Chemical Society , 2012
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationSíntesi orgànica
dc.subject.classificationLactames
dc.subject.classificationEnantiòmers
dc.subject.classificationCompostos heterocíclics
dc.subject.otherOrganic synthesis
dc.subject.otherLactams
dc.subject.otherEnantiomers
dc.subject.otherHeterocyclic compounds
dc.titleA practical synthetic route to enantiopure 6-substituted cis-decahydroquinolines
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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