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2018

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/127602

Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones

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Abstract

In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been developed.

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https://doi.org/10.2174/1570178615666171213143657

Subject

Alcaloides, Lactames, Síntesi asimètrica

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Alkaloids, Lactams, Asymmetric synthesis

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Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

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GRIERA FARRES, Rosa, et al. Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones. Letters In Organic Chemistry. 2018. Vol. 15, num. 5, pags. 335-339. ISSN 1570-1786. [consulted: 8 of October of 2026]. Available at: https://hdl.handle.net/2445/127602

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