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2023-10-19

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cc-by (c) Hernández-García, M et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/221176

Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study.

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https://doi.org/10.3390/children10101703

Resum

SARS-CoV-2 pneumonia in children has a lower incidence and severity compared to adults. Risk factors are adolescence and comorbidities. Our aims were to describe the characteristics of children admitted with SARS-CoV-2 pneumonia, identify risk factors associated with severity and compare the cases according to the variant of SARS-CoV-2. This was a descriptive and retrospective study, including patients aged 0-18 years hospitalized in a tertiary-care hospital between l March 2020 and l March 2022. Epidemiological, clinical, diagnostic and therapeutic data were analyzed. Forty-four patients were admitted; twenty-six (59%) were male and twenty-seven (61 %) were older than 12 years. Thirty-six (82%) had comorbidities, the most frequent of which were obesity and asthma. Seven (15.9%) patients required high-flow oxygen, eleven (25%) non-invasive ventilation and four (9.1 %) conventional mechanical ventilation. In critically ill patients, higher levels of anemia, lymphopenia, procalcitonin, lactate dehydrogenase (LDH) and hypoalbuminemia and lower levels of HDL-cholesterol were detected (all p < 0.05). Prematurity (p = 0.022) was associated with intensive care unit adrnission. Patients were younger during the Omicron wave (p < O.Ol); no variant was associated with greater severity. In conclusion, pediatric patients with a history of prematurity or with anemia, lymphopenia, elevated procalcitonin, elevated LDH levels, hypoalbuminemia and low HDL-cholesterol levels may require admission and present more severe forms. Apart from age, no notable differences between SARS-CoV-2 variant periods were found.

Matèries

Factors de risc en les malalties, Pneumònia, SARS-CoV-2, COVID-19, Pediatria

Matèries (anglès)

Risk factors in diseases, Pneumonia, SARS-CoV-2, COVID-19, Pediatrics

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Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)

Citació

HERNÁNDEZ GARCÍA, María, et al. Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study. Children. 2023. Vol. 10, num. 10, pags. 1703. ISSN 2227-9067. [consulted: 18 of August of 2026]. Available at: https://hdl.handle.net/2445/221176

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