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cc-by (c) Hernández-García, M et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/221176

Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study.

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SARS-CoV-2 pneumonia in children has a lower incidence and severity compared to adults. Risk factors are adolescence and comorbidities. Our aims were to describe the characteristics of children admitted with SARS-CoV-2 pneumonia, identify risk factors associated with severity and compare the cases according to the variant of SARS-CoV-2. This was a descriptive and retrospective study, including patients aged 0-18 years hospitalized in a tertiary-care hospital between l March 2020 and l March 2022. Epidemiological, clinical, diagnostic and therapeutic data were analyzed. Forty-four patients were admitted; twenty-six (59%) were male and twenty-seven (61 %) were older than 12 years. Thirty-six (82%) had comorbidities, the most frequent of which were obesity and asthma. Seven (15.9%) patients required high-flow oxygen, eleven (25%) non-invasive ventilation and four (9.1 %) conventional mechanical ventilation. In critically ill patients, higher levels of anemia, lymphopenia, procalcitonin, lactate dehydrogenase (LDH) and hypoalbuminemia and lower levels of HDL-cholesterol were detected (all p < 0.05). Prematurity (p = 0.022) was associated with intensive care unit adrnission. Patients were younger during the Omicron wave (p < O.Ol); no variant was associated with greater severity. In conclusion, pediatric patients with a history of prematurity or with anemia, lymphopenia, elevated procalcitonin, elevated LDH levels, hypoalbuminemia and low HDL-cholesterol levels may require admission and present more severe forms. Apart from age, no notable differences between SARS-CoV-2 variant periods were found.

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HERNÁNDEZ GARCÍA, María, SOLITO, Claudia, PAVÓN ORTIZ, Alba, ARGUEDAS CASAMAYOR, Noelia, MELÉ CASAS, Maria, PONS TOMÀS, Gemma, FERNÁNDEZ DE SEVILLA ESTRACH, Mariona, PINO RAMÍREZ, Rosa maría, LAUNES MONTAÑA, Cristian, GUITART, Carmina, GIRONA ALARCÓN, Mònica, JORDÁN GARCÍA, Iolanda, GARCÍA GARCÍA, Juan josé. Characteristics and Risk Factors Associated with SARS-CoV-2 Pneumonias in Hospitalized Pediatric Patients: A Pilot Study.. _Children_. 2023. Vol. 10, núm. 10, pàgs. 1703. [consulta: 23 de gener de 2026]. ISSN: 2227-9067. [Disponible a: https://hdl.handle.net/2445/221176]

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