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2017-10-24

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cc by (c) Lufele et al., 2017
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/117491

Risk factors and pregnancy outcomes associated with placental malaria in a prospective cohort of Papua New Guinean women

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http://dx.doi.org/10.1186/s12936-017-2077-4

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BACKGROUND: Plasmodium falciparum in pregnancy results in substantial poor health outcomes for both mother and child, particularly in young, primigravid mothers who are at greatest risk of placental malaria (PM) infection. Complications of PM include maternal anaemia, low birth weight and preterm delivery, which contribute to maternal and infant morbidity and mortality in coastal Papua New Guinea (PNG). METHODS: Placental biopsies were examined from 1451 pregnant women who were enrolled in a malaria prevention study at 14-26 weeks gestation. Clinical and demographic information were collected at first antenatal clinic visits and women were followed until delivery. Placental biopsies were collected and examined for PM using histology. The presence of infected erythrocytes and/or the malaria pigment in monocytes or fibrin was used to determine the type of placental infection. RESULTS: Of 1451 placentas examined, PM infection was detected in 269 (18.5%), of which 54 (3.7%) were acute, 55 (3.8%) chronic, and 160 (11.0%) were past infections. Risk factors for PM included residing in rural areas (adjusted odds ratio (AOR) 3.65, 95% CI 1.76-7.51; p

Matèries

Malària, Embaràs, Papua Nova Guinea

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Malaria, Pregnancy, Papua New Guinea

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Articles publicats en revistes (ISGlobal)
Articles publicats en revistes (Fonaments Clínics)

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LUFELE, Elvin, UMBERS, Alexandra j., ORDI I MAJÀ, Jaume, OME-KAIUS, Maria, WANGNAPI, Regina a., UNGER, Holger werner, TARONGKA, Nandao, SIBA, Peter, MUELLER, Ivo, ROBINSON, Leanne j., ROGERSON, Stephen john. Risk factors and pregnancy outcomes associated with placental
                malaria in a prospective cohort of Papua New Guinean women. _Malaria Journal_. 2017. Vol. 16, núm. 1, pàgs. 427. [consulta: 14 de gener de 2026]. ISSN: 1475-2875. [Disponible a: https://hdl.handle.net/2445/117491]

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