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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/157340

Fluoquinolone resistance in Streptococcus pneumoniae

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To the Editor: Chen et al. (July 22 issue) report an increasing prevalence of Streptococcus pneumoniae strains with reduced susceptibility to fluoroquinolones in Canada. We have found similar results in Barcelona, Spain.Of 2822 pneumococcal isolates studied in our institution from 1991 through 1998, 57 (2.0 percent) were resistant to ciprofloxacin (minimal inhibitory concentration, ≥4 μg per milliliter). We have seen an increase of ciprofloxacin-resistant pneumococci, from 0.9 percent (6 of 675 strains) in 1991-1992 to 3.0 percent (22 of 727 strains) in 1997-1998 (P=0.004).

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LIÑARES LOUZAO, Josefina, CAMPA, Adela G. de la and PALLARÉS GINER, Roman. Fluoquinolone resistance in Streptococcus pneumoniae. New England Journal of Medicine. 1999. Vol. 341, num. 15, pags. 1546-1548. ISSN 0028-4793. [consulted: 18 of June of 2026]. Available at: https://hdl.handle.net/2445/157340

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