Miniatura

Fitxers

723216.pdf (1.05 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2022-03-17

Llicència de publicació

cc-by (c) Guitart, Carmina et al., 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/195851

Risk factors and incidence of invasive bacterial infection in severe bronchiolitis: the RICOIB prospective study

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1186/s12887-022-03206-4

Resum

Background: Bacterial infection (BI), both community-acquired (CA-BI) and hospital-acquired (HAI), might present as a severe complication in patients with bronchiolitis. This study aimed to describe BI in children with severe bronchiolitis, and to define risk factors for BI. Methods: This was a prospective, descriptive study that included infants admitted to the pediatric intensive care unit (PICU) due to bronchiolitis between 2011 and 2017. The BROSJOD score was calculated to rate the severity of bronchiolitis. Results: Inclusion of 675 patients, with a median age of 47 days (IQR 25-99). 175 (25.9%) patients developed BI, considered HAI in 36 (20.6%). Patients with BI had higher BROSJOD score, PRISM III, and required invasive mechanical ventilation and inotropic support more frequently (p < 0.001). BI was independently associated with BROSJOD higher than 12 (OR 2.092, 95%CI 1.168-3.748) CA-BI was associated to BROSJOD > 12 (OR 2.435, 95%CI 1.379-4.297) and bacterial co-infection (OR 2.294 95%CI 1.051-5.008). Concerning HAI, an independent association was shown with mechanical ventilation longer than 7 days (OR 5.139 95%CI 1.802-14.652). Infants with BI had longer PICU and hospital stay (p < 0.001), Mortality was higher in patients with HAI. Conclusions: A quarter of infants with severe bronchiolitis developed BI. A BROSJOD > 12 may alert the presence of CA-BI, especially pneumonia. Patients with BI have higher morbidity and mortality.

Matèries

Malalties de l'aparell respiratori en els infants, Bacteris, Infeccions en els infants, Pneumònia adquirida a la comunitat, Factors de risc en les malalties

Matèries (anglès)

Respiratory diseases in children, Bacteria, Infection in children, Community-acquired pneumonia, Risk factors in diseases

Citació

Col·leccions

Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)

Citació

GUITART, Carmina, ALEJANDRE, Carme, BOBILLO PÉREZ, Sara, GIRONA ALARCÓN, Mònica, SOLÉ RIBALTA, Anna, CAMBRA LASAOSA, Francisco josé, BALAGUER GARGALLO, Mònica, JORDÁN GARCÍA, Iolanda. Risk factors and incidence of invasive bacterial infection in severe bronchiolitis: the RICOIB prospective study. _BMC Pediatrics_. 2022. Vol. 22, núm. 1, pàgs. 140. [consulta: 23 de gener de 2026]. ISSN: 1471-2431. [Disponible a: https://hdl.handle.net/2445/195851]

Exportar metadades

JSON - METS

Compartir registre