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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/152359
Taking the 'I' out of LLINs: using insecticides in vector control tools other than long-lasting nets to fight malaria
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Long-lasting insecticidal nets, or LLINs, have
significantly reduced malaria morbidity and mortality over the
past two decades. The net provides a physical barrier that
decreases human-mosquito contact and the impregnated insecticide
kills susceptible mosquito vectors upon contact and may repel
them. However, the future of LLINs is threatened as resistance
to pyrethroids is now widespread, the chemical arsenal for LLINs
is very limited, time from discovery of next-generation
insecticides to market is long, and persistent transmission is
frequently caused by vector populations avoiding contact with
LLINs. Here we ask the question whether, given these challenges,
insecticides should be incorporated in nets at all. We argue
that developing long-lasting nets without insecticide(s) can
still reduce vector populations and provide both personal and
community protection, if combined with other approaches or
technologies. Taking the insecticide out of the equation (i)
allows for a faster response to the current pyrethroid
resistance crisis, (ii) avoids an LLIN-treadmill aimed at
replacing failing bed nets due to insecticide resistance, and
(iii) permits the utilization of our current and future
insecticidal arsenal for other vector control tools to target
persistent malaria transmission.
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PAAIJMANS, Krijn p., HUIJBEN, Silvie. Taking the 'I' out of LLINs: using insecticides in vector control tools other than long-lasting nets to fight malaria. _Malaria Journal_. 2020. Vol. 19. [consulta: 21 de gener de 2026]. ISSN: 1475-2875. [Disponible a: https://hdl.handle.net/2445/152359]