Synthesis of Sr-Mg-Zn co-substituted hydroxyapatite

Abstract

Nowadays, many developed nations have aging population which has led to an up growth of demand of artificial joints prostheses. With the increasing needs of bone implants, the academic community is focusing on improving the mechanical and biological properties of implants. Bone is mainly composed by hydroxyapatite, and that is the reason why hydroxyapatite is known as a stable material for coating orthopaedic implants surface. Hydroxyapatite provides an excellent biocompatibility to the implant and enhances osseointegration. However, once the use of Hap has extended, some limitations and complications have arisen such as low biological interaction. Modifying hydroxyapatite by ionic substitution, in order to resemble compositions of hydroxyapatite and bone, has emerged as a solution...