Carregant...
Miniatura

Tipus de document

Article

Versió

Versió publicada

Data de publicació

Llicència de publicació

cc by (c) Cova et al., 2015
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/69164

Sugar activation and glycosylation in Plasmodium

Títol de la revista

Director/Tutor

ISSN de la revista

Títol del volum

Resum

Glycoconjugates are important mediators of host-pathogen interactions and are usually very abundant in the surface of many protozoan parasites. However, in the particular case of Plasmodium species, previous works show that glycosylphosphatidylinositol anchor modifications, and to an unknown extent, a severely truncated N-glycosylation are the only glycosylation processes taking place in the parasite. Nevertheless, a detailed analysis of the parasite genome and the recent identification of the sugar nucleotide precursors biosynthesized by Plasmodium falciparum support a picture in which several overlooked, albeit not very prominent glycosylations may be occurring during the parasite life cycle. In this work, the authors review recent developments in the characterization of the biosynthesis of glycosylation precursors in the parasite, focusing on the outline of the possible fates of these precursors.

Citació

Citació

COVA, Marta, RODRIGUES, Joao a., SMITH, Terry k., IZQUIERDO LÁZARO, Luis. Sugar activation and glycosylation in Plasmodium. _Malaria Journal_. 2015. Vol. 14, núm. 1, pàgs. 427. [consulta: 21 de gener de 2026]. ISSN: 1475-2875. [Disponible a: https://hdl.handle.net/2445/69164]

Exportar metadades

JSON - METS

Compartir registre