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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/127829
Nucleic acid i-motif structures in analytical chemistry
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Under the appropriate experimental conditions of pH and temperature, cytosine-rich segments in DNA or RNA sequences may produce a characteristic folded structure known as an i-motif. Besides its potential role in vivo, which is still under investigation, this structure has attracted increasing interest in other fields due to its sharp, fast and reversible pH-driven conformational changes. This 'on/off' switch at molecular level is being used in nanotechnology and analytical chemistry to develop nanomachines and sensors, respectively. This paper presents a review of the latest applications of this structure in the field of chemical analysis.
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ALBA, Juan Josep, SADURNÍ, Anna and GARGALLO GÓMEZ, Raimundo. Nucleic acid i-motif structures in analytical chemistry. Critical Reviews in Analytical Chemistry. 2016. Vol. 46, num. 5. ISSN 1040-8347. [consulted: 5 of October of 2026]. Available at: https://hdl.handle.net/2445/127829