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2010-02-02

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/52926

Effect of maternal clinical chorioamnionitis on neonatal morbidity in very-low birthweight infants: a case control study

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http://dx.doi.org/10.1515/JPM.2010.029

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Aims: To assess the relationship between maternal clinical chorioamnionitis and neonatal outcome in preterm very-low birthweight (VLBW) infants. Methods: An observational case-control study was conducted in the Neonatology Services of 12 acute-care teaching hospitals in Spain. Between January 2004 and December 2006, all consecutive VLBW (F1500 g) infants born to a mother with clinical chorioamnionitis were enrolled. Controls were infants without chorioamnionitis matched by gestational age who were born immediately after each index case. Results: There were 165 cases and 163 controls. A significantly higher percentage of cases than controls required intubation (53% vs. 35.8%), had normal intrauterine growth (98.1% vs. 84.7%), were born in a tertiary center (inborn) (95.1% vs. 89.1%), from single gestations (76.4% vs. 65.6%) and vaginal delivery (47.3% vs. 33.3%), showed a lowerApgar score at 5 min, and presented a higher rate of earlyonset sepsis (10.4% vs. 1.2%). Older maternal age (32.5 vs. 30.8 years), premature labor (67.3% vs. 25.8%), premature rupture of membranes (61.3% vs. 25.8%), and antibiotic treatment (88.5% vs. 52.3%) were significantly more frequent among cases than controls. Conclusions: After controlling by gestational age, maternal chorioamnionitis was associated with neonatal depression and early sepsis but not with other prematurity-related complications.

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Diagnòstic prenatal, Infants prematurs, Neonatologia

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Prenatal diagnosis, Premature infants, Neonatology

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BOTET MUSSONS, Francisco, FIGUERAS ALOY, José, CARBONELL I ESTRANY, Xavier, ARCA DÍAZ, Gemma, Castrillo Study Group. Effect of maternal clinical chorioamnionitis on neonatal morbidity in very-low birthweight infants: a case control study. _Journal of Perinatal Medicine_. 2010. Vol. 38, núm. 3, pàgs. 269-273. [consulta: 30 de gener de 2026]. ISSN: 0300-5577. [Disponible a: https://hdl.handle.net/2445/52926]

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