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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/99566
Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms
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OBJECTIVE: To characterize two Achromobacter xylosoxidans
recovered from 2 patients diagnosed with pertussis during a
Bordetella pertussis surveillance program. METHODS:
Nasopharyngeal swabs from 2 children under 1 year of age with
clinical suspicion of pertussis were analyzed by culture and
PCR. RESULTS: Two Achromobacter xylosoxidans A8, closely related
to Bordetella spp. were recovered from 2 patients diagnosed of
pertussis, both carrying the ptxA gene and IS418 the pertussis
toxin encoding gene. Subsequently, antibiotic susceptibility was
evaluated by disk-diffusion method and by PCR. CONCLUSIONS:
Although more detailed studies are needed, the present data
highlight the possibility that Achromobacter xylosoxidans,
closely related Bordetella pertusssis microorganisms and not
covered under the vaccine umbrella, might also result in cases
of whooping cough. Thereby further surveillance is necessary to
determine the extension and relevance of their pathogenic role
in order to discriminate their real public health implication.
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ORELLANA-PERALTA, Fiorella, et al. Characterization of two Achromobacter xylosoxidans isolates from
patients with pertussis-like symptoms. Asian Pacific Journal of Tropical Medicine. 2015. Vol. 8, num. 6, pags. 464-467. ISSN 1995-7645. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/99566