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cc by-nc-nd (c) Elsevier, 2015
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/99566

Characterization of two Achromobacter xylosoxidans isolates from patients with pertussis-like symptoms

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OBJECTIVE: To characterize two Achromobacter xylosoxidans recovered from 2 patients diagnosed with pertussis during a Bordetella pertussis surveillance program. METHODS: Nasopharyngeal swabs from 2 children under 1 year of age with clinical suspicion of pertussis were analyzed by culture and PCR. RESULTS: Two Achromobacter xylosoxidans A8, closely related to Bordetella spp. were recovered from 2 patients diagnosed of pertussis, both carrying the ptxA gene and IS418 the pertussis toxin encoding gene. Subsequently, antibiotic susceptibility was evaluated by disk-diffusion method and by PCR. CONCLUSIONS: Although more detailed studies are needed, the present data highlight the possibility that Achromobacter xylosoxidans, closely related Bordetella pertusssis microorganisms and not covered under the vaccine umbrella, might also result in cases of whooping cough. Thereby further surveillance is necessary to determine the extension and relevance of their pathogenic role in order to discriminate their real public health implication.

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ORELLANA-PERALTA, Fiorella, JACINTO, Michelle, PONS, Maria j., GOMES, Cláudia, BADA, Carlos, REYES, Isabel, VALLE MENDOZA, Juana del, RUIZ, Joaquim. Characterization of two Achromobacter xylosoxidans isolates from
                patients with pertussis-like symptoms. _Asian Pacific Journal of Tropical Medicine_. 2015. Vol. 8, núm. 6, pàgs. 464-467. [consulta: 20 de gener de 2026]. ISSN: 1995-7645. [Disponible a: https://hdl.handle.net/2445/99566]

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