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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/178384
Validation of the STN-DBS intervention as a treatment for Parkinson's disease by studying the accuracy of electrode placement and possible correlation with motor symptoms
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Abstract
Parkinson’s disease is present approximately in 10 million individuals all over the world, being
one of the most common neurodegenerative diseases, and statistics denote that its prevalence
will raise in the coming years. Deep brain stimulation is an effective surgical treatment for patients
who do not improve with drug treatment and who present many motor symptoms. Deep brain
stimulation constitutes the implantation of electrodes in specific brain structures, nevertheless,
this study has focused on the subthalamic nucleus, being the main target region for Parkinson’s
disease. In order to have satisfactory post-surgical results, where the patient has a considerable
reduction in motor symptoms, it is essential to present a correct lead placement accuracy, which
corresponds with what has been planned before surgery by terms of using the neuronavigator.
The principal objective of this study is to validate the accuracy of the actual technique used in the
Hospital Clínic of Barcelona, which is guided exclusively by image, as well as to establish a
possible relationship between the patient's clinic, following the UPDRS scale type III, once it has
undergone surgery and the accuracy of the electrodes, to verify that it essential to achieve its
maximum effectiveness. Thus, objective arguments of the image-guided and image-verified
technique can also be given as well as providing assertion of completing the procedure with the
patient completely anaesthetised, since currently in Catalonia most centres do so with the patient
awake and with microelectrode recording...
Description
Treballs Finals de Grau d'Enginyeria Biomèdica. Facultat de Medicina i Ciències de la Salut. Universitat de Barcelona. Curs: 2020-2021. Director: Jordi Rumià Arboix. Tutor: Agustí Gutiérrez Gálvez.
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GUILLOT VIDAL, Ilianne. Validation of the STN-DBS intervention as a treatment for Parkinson's disease by studying the accuracy of electrode placement and possible correlation with motor symptoms. [consulted: 8 of August of 2026]. Available at: https://hdl.handle.net/2445/178384