Piperaquine Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers of Papua New Guinea after Administration of Three-Monthly Doses of Dihydroartemisinin–Piperaquine

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dc.contributor.authorMillat Martínez, Pere
dc.contributor.authorSalman, Sam
dc.contributor.authorMoore, Brioni R.
dc.contributor.authorBaró Sastre, Bàrbara
dc.contributor.authorPage-Sharp, Madhu
dc.contributor.authorBatty, Kevin T.
dc.contributor.authorRobinson, Leanne J.
dc.contributor.authorPomat, William
dc.contributor.authorKarunajeewa, Harin
dc.contributor.authorLaman, Moses
dc.contributor.authorManning, Laurens
dc.contributor.authorMitjà Villar, Oriol
dc.contributor.authorBassat Orellana, Quique
dc.date.accessioned2023-09-21T10:42:35Z
dc.date.available2023-09-21T10:42:35Z
dc.date.issued2022-07-06
dc.date.updated2023-09-21T09:56:14Z
dc.description.abstractMass drug administration (MDA) with monthly dihydroartemisinin-piperaquine (DHA-PQP) appears useful in malaria control and elimination strategies. Determining the relationship between consecutive piperaquine phosphate (PQP) exposure and its impact on QT interval prolongation is a key safety consideration for MDA campaigns.
dc.format.extent25 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idimarina9693224
dc.identifier.issn1098-6596
dc.identifier.pmid35862743
dc.identifier.urihttps://hdl.handle.net/2445/202127
dc.language.isoeng
dc.publisherAmerican Society for Microbiology
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1128/aac.00185-22
dc.relation.ispartofAntimicrobial Agents And Chemotherapy, 2022, vol. 66, num. 8
dc.relation.urihttps://doi.org/10.1128/aac.00185-22
dc.rights(c) American Society for Microbiology, 2022
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (ISGlobal)
dc.subject.classificationMalària
dc.subject.classificationFarmacocinètica
dc.subject.classificationPapua Nova Guinea
dc.subject.otherMalaria
dc.subject.otherPharmacokinetics
dc.subject.otherPapua New Guinea
dc.titlePiperaquine Pharmacokinetic and Pharmacodynamic Profiles in Healthy Volunteers of Papua New Guinea after Administration of Three-Monthly Doses of Dihydroartemisinin–Piperaquine
dc.typeinfo:eu-repo/semantics/article

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