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Ortiz Miquel Olga.pdf (399.17 KB)

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Bachelor thesis

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2018-06

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cc-by-nc-nd (c) Ortiz, 2018
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/125149

Spontaneous activity in neuronal networks with dictated connectivity

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We studied spontaneous activity in rat neuronal cultures and compared two configurations, namely homogeneous and patterned. In the former, neurons grew over a plain glass substrate and therefore could develop isotropically. In the latter, neurons grew on a substrate shaped with topographical obstacles, which dictated the connectivity of the neurons and broke the isotropy of the system. Activity in all networks was recorded using fluorescence calcium imaging. By analyzing and comparing their activity patterns, we have found that activity in patterned cultures is markedly different, with richer spatiotemporal activity fronts and slower propagation speeds.

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Jordi Soriano Fradera

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Xarxes neuronals (Neurobiologia), Cultiu cel·lular, Treballs de fi de grau

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Neural networks (Neurobiology), Cell culture, Bachelor's theses

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Treballs Finals de Grau (TFG) - Física

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ORTIZ MIQUEL, Olga. Spontaneous activity in neuronal networks with dictated connectivity. [consulted: 8 of October of 2026]. Available at: https://hdl.handle.net/2445/125149

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