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2022-06-17

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cc-by (c) Castillo Delgado, Carlos Alfredo et al., 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/200334

Orthotopic kidney transplantation survival and complications: systematic review and meta-analysis

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https://doi.org/10.1080/2090598X.2022.2090133

Abstract

Purpose: To determine graft and patient survival and adverse events in patients who undergo orthotopic kidney transplantation. Methods: We performed a systematic review and meta-analysis. We search in Medline, Embase, and Central from inception to nowadays. We included observational studies with patients who undergo orthotopic kidney transplantation. The primary outcomes were overall patient and graft survival. We pooled the information in a frequency meta-analysis with a 95% CI. We analyzed bias with the STROBE statement. Results: Of the 106 papers initially retrieved, four met the inclusion criteria. Vascular and urinary tract complications were reported in 19% and 15%, respectively. The overall patient survival was 92% 95%CI (88% to 95%), I2 = 0%, and the overall graft survival was 88% 95 CI (83% to 91%), I2 = 0%. Conclusion: Our analysis showed a high survival rate in patients and kidney grafts after orthotopic kidney transplantation, with a similar complication rate compared to a heterotopic kidney transplant.

Subject

Trasplantament renal, Malalties del ronyó, Rebuig (Biologia), Metaanàlisi, Anàlisi de supervivència (Biometria), Ressenyes sistemàtiques (Investigació mèdica)

Subject (English)

Kidney transplantation, Kidney diseases, Graft rejection, Meta-analysis, Survival analysis (Biometry), Systematic reviews (Medical research)

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Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

CASTILLO DELGADO, Carlos Alfredo, et al. Orthotopic kidney transplantation survival and complications: systematic review and meta-analysis. Arab Journal of Urology. 2022. Vol. 20, num. 4, pags. 212-218. ISSN 2090-5998. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/200334

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