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cc by (c) Elsevier, 2017
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/118598

Low birth weight: Case definition & guidelines for data collection, analysis, and presentation of maternal immunization safety data

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Need for developing case definitions and guidelines for data collection, analysis, and presentation for low birth weight as an adverse event following maternal immunization The birth weight of an infant is the first weight recorded after birth, ideally measured within the first hours after birth, before significant postnatal weight loss has occurred. Low birth weight (LBW) is defined as a birth weight of less than 2500 g (up to and including 2499 g), as per the World Health Organization (WHO) [1]. This definition of LBW has been in existence for many decades. In 1976, the 29th World Health Assembly agreed on the currently used definition. Prior to this, the definition of LBW was ‘2500 g or less’. Low birth weight is further categorized into very low birth weight (VLBW, <1500 g) and extremely low birth weight (ELBW, <1000 g) [1]. Low birth weight is a result of preterm birth (PTB, short gestation <37 completed weeks), intrauterine growth restriction (IUGR, also known as fetal growth restriction), or both. The term low birth weight refers to an absolute weight of <2500 g regardless of gestational age. Small for gestational age (SGA) refers to newborns whose birth weight is less than the 10th percentile for gestational age. This report will focus specifically on birth weight <2500 g. Further details related to case definitions for PTB [2], IUGR and SGA are included in separate GAIA reports.

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CUTLAND, Clare L., et al. Low birth weight: Case definition & guidelines for data
                collection, analysis, and presentation of maternal immunization
                safety data. Vaccine. 2017. Vol. 35, num. 48 Pt A, pags. 6492-6500. ISSN 0264-410X. [consulted: 10 of June of 2026]. Available at: https://hdl.handle.net/2445/118598

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