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cc-by (c) Hessheimer, Amelia Judith et al., 2019
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/158059

Somatostatin and the 'Small-For-Size' Liver

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"Small-for-size" livers arising in the context of liver resection and transplantation are vulnerable to the effects of increased portal flow in the immediate postoperative period. Increased portal flow is an essential stimulus for liver regeneration. If the rise in flow and stimulus for regeneration are excessive; however, liver failure and patient death may result. Somatostatin is an endogenous peptide hormone that may be administered exogenously to not only reduce portal blood flow but also offer direct protection to different cells in the liver. In this review article, we describe key changes that transpire in the liver following a relative size reduction occurring in the context of resection and transplantation and the largely beneficial effects that peri-operative somatostatin therapy may help achieve in this setting.

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HESSHEIMER, Amelia judith, MARTÍNEZ DE LA MAZA, Lilia, ADEL AL SHWELY, Farah, ESPINOZA, Arlena sofía, AUSANIA, Fabio, FONDEVILA CAMPO, Constantino. Somatostatin and the 'Small-For-Size' Liver. _International Journal of Molecular Sciences_. 2019. Vol. 20, núm. 10, pàgs. 2512. [consulta: 23 de febrer de 2026]. ISSN: 1661-6596. [Disponible a: https://hdl.handle.net/2445/158059]

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