Document type
ArticleVersion
Published versionPublication date
All rights reserved
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/178416
Experimental study on radioactive pathways of hypodermically injected technetium-99m
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
The objective of this study was to investigate the biological substrate of radioactive pathways of migration of hypodermically injected 99mTc into points of low electrical resistance. Sixteen anesthetized adult male beagles were used. Control and test points were defined by comparing their electrical resistance to that of the pinna. Seventy-three experiments of three different types were performed: (1) separate hypodermic injections of [99mTc] sodium pertechnetate, 201Tl-chloride, 131INa and 99mTc-rhenium sulfide into control and test points; (2) simultaneous injections of [99mTc]sodium pertechnetate and 201Tl chloride into control and test points; and (3) intravascular injections of 99mTcO4 into blood vessels underlying test points. Only the hypodermic injection of 99mTc into points of low electrical resistance gave rise to a specific radioactive pathway characterized by rapid and longitudinal migration, clearly independent of background activity. The specific radioactive pathway detected is not the result of diffusion of the radiotracer through nerves, veins or lymphatic vessels, but its trajectory coincides with that described for one of the acupuncture meridians in the dog.
Subject (English)
Citation
Citation
KOVACS, Francisco M., et al. Experimental study on radioactive pathways of hypodermically injected technetium-99m. Journal of Nuclear Medicine. 1992. Vol. 33, num. 3, pags. 403-407. ISSN 0161-5505. [consulted: 6 of June of 2026]. Available at: https://hdl.handle.net/2445/178416