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092795.pdf (1019.31 KB)

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1992-03-01

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/178416

Experimental study on radioactive pathways of hypodermically injected technetium-99m

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The objective of this study was to investigate the biological substrate of radioactive pathways of migration of hypodermically injected 99mTc into points of low electrical resistance. Sixteen anesthetized adult male beagles were used. Control and test points were defined by comparing their electrical resistance to that of the pinna. Seventy-three experiments of three different types were performed: (1) separate hypodermic injections of [99mTc] sodium pertechnetate, 201Tl-chloride, 131INa and 99mTc-rhenium sulfide into control and test points; (2) simultaneous injections of [99mTc]sodium pertechnetate and 201Tl chloride into control and test points; and (3) intravascular injections of 99mTcO4 into blood vessels underlying test points. Only the hypodermic injection of 99mTc into points of low electrical resistance gave rise to a specific radioactive pathway characterized by rapid and longitudinal migration, clearly independent of background activity. The specific radioactive pathway detected is not the result of diffusion of the radiotracer through nerves, veins or lymphatic vessels, but its trajectory coincides with that described for one of the acupuncture meridians in the dog.

Matèries

Tecneci, Farmacocinètica, Injeccions hipodèrmiques

Matèries (anglès)

Technetium, Pharmacokinetics, Hypodermic injections

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Articles publicats en revistes (Patologia i Terapèutica Experimental)

Citació

KOVACS, Francisco m., GÖTZENS GARCÍA, Víctor josé, GARCIA, Alicía, GARCÍA, Félix, MUFRAGGI, Nicole, PRANDI, David, SETOAIN PEREGO, Xavier, SAN ROMÁN, Fidel. Experimental study on radioactive pathways of hypodermically injected technetium-99m. _Journal of Nuclear Medicine_. 1992. Vol. 33, núm. 3, pàgs. 403-407. [consulta: 6 de maig de 2026]. ISSN: 0161-5505. [Disponible a: https://hdl.handle.net/2445/178416]

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