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Herrera Carrillo Jose Arnau.pdf (1.89 MB)

Document type

Bachelor thesis

Publication date

2018-06

Publication license

cc-by-nc-nd (c) Herrera, 2018
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/125071

Initiation and propagation of activity in neuronal cultures under connectivity alterations

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Abstract

Activity in living neuronal networks is governed by complex laws that are still poorly understood. To advance in this quest, we study the initiation and propagation of activity fronts in in vitro neuronal networks. We consider two major experiments in which we modify the connectivity of the network. In a first one, we physically cut a region of the culture. I a second one we apply a drug that changes the connectivity of the network. In both experiments, we determine the velocity of the activity fronts, their timing and the point of origin. We frame our results in the context of the noise focusing phenomena, a mechanism that explains the initiation of activity in terms of network connectivity, neuronal dynamics, and amplification of noise

Description

Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2018, Tutor: Jordi Soriano Fradera

Subject

Xarxes neuronals (Neurobiologia), Soroll, Treballs de fi de grau

Subject (English)

Neural networks (Neurobiology), Noise, Bachelor's theses

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Treballs Finals de Grau (TFG) - Física

Citation

HERRERA CARRILLO, Jose Arnau. Initiation and propagation of activity in neuronal cultures under connectivity alterations. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/125071

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