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Caught in action: visualizing dynamic nanostructures within supramolecular systems chemistry

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Supramolecular systems chemistry has been an area of active research to develop nanomaterials with life-like functions. Progress in systems chemistry relies on our ability to probe the nanostructure formation in solution. Often visualizing the dynamics of nanostructures which transform over time is a formidable challenge. This necessitates a paradigm shift from dry sample imaging towards solution-based techniques. We review the application of state-of-the-art techniques for real-time, in situ visualization of dynamic self-assembly processes. We present how solution-based techniques namely optical super-resolution microscopy, solution-state atomic force microscopy, liquid-phase transmission electron microscopy, molecular dynamics simulations and other emerging techniques are revolutionizing our understanding of active and adaptive nanomaterials with life-like functions. This Review provides the visualization toolbox and futuristic vision to tap the potential of dynamic nanomaterials.

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VENUGOPAL, Venugopal, RUIZ-PEREZ, Lorena, SWAMYNATHAN, K., KULKARNI, Chidambar, CALÒ, Annalisa, KUMAR, Mohit. Caught in action: visualizing dynamic nanostructures within supramolecular systems chemistry. _Angewandte Chemie-International Edition_. 2022. Vol. 62, núm. 8. [consulta: 5 de maig de 2026]. ISSN: 1433-7851. [Disponible a: https://hdl.handle.net/2445/193373]

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