Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

White adipose tissue dysfunction in obesity and aging

Vista senzilla d'ítem
dc.contributor.authorReyes-Bossio, Mario
dc.contributor.authorFos Domènech, Júlia
dc.contributor.authorSerra i Cucurull, Dolors
dc.contributor.authorHerrero Rodríguez, Laura
dc.contributor.authorSánchez-Infantes, David
dc.date.accessioned2026-06-29T15:06:54Z
dc.date.available2026-06-29T15:06:54Z
dc.date.issued2021
dc.date.updated2026-06-29T15:06:55Z
dc.description.abstractBoth obesity and aging are associated with the development of metabolic diseases such as type 2 diabetes and cardiovascular disease. Chronic low-grade inflammation of adipose tissue is one of the mechanisms implicated in the progression of these diseases. Obesity and aging trigger adipose tissue alterations that ultimately lead to a pro-inflammatory phenotype of the adipose tissue-resident immune cells. Obesity and aging also share other features such as a higher visceral vs. subcutaneous adipose tissue ratio and a decreased lifespan. Here, we review the common characteristics of obesity and aging and the alterations in white adipose tissue and resident immune cells. We focus on the adipose tissue metabolic derangements in obesity and aging such as inflammation and adipose tissue remodeling.
dc.format.extent12 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec714699
dc.identifier.issn0006-2952
dc.identifier.pmid34364887
dc.identifier.urihttps://hdl.handle.net/2445/230270
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.bcp.2021.114723
dc.relation.ispartofBiochemical Pharmacology, 2021, vol. 192
dc.relation.urihttps://doi.org/10.1016/j.bcp.2021.114723
dc.rightscc-by (c) Reyes-Bossio, Mario et al., 2021
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Bioquímica i Fisiologia)
dc.subject.classificationTeixit adipós
dc.subject.classificationTrastorns de la nutrició en les persones grans
dc.subject.otherAdipose tissues
dc.subject.otherNutrition disorders in old age
dc.titleWhite adipose tissue dysfunction in obesity and aging
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
242002.pdf
Mida:
2.8 MB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Bioquímica i Fisiologia)