PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders

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dc.contributor.authorPalomer Tarridas, Francesc Xavier
dc.contributor.authorBarroso Fernández, Emma
dc.contributor.authorPizarro Delgado, Javier
dc.contributor.authorPeña, Lucía
dc.contributor.authorBotteri, Gaia
dc.contributor.authorZarei, Mohammad
dc.contributor.authorAguilar, David
dc.contributor.authorMontori Grau, Marta
dc.contributor.authorVázquez Carrera, Manuel
dc.date.accessioned2020-04-27T15:00:52Z
dc.date.available2020-04-27T15:00:52Z
dc.date.issued2018-03-20
dc.date.updated2020-04-27T15:00:52Z
dc.description.abstractResearch in recent years on peroxisome proliferator-activated receptor (PPAR)β/δ indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARβ/δ activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARβ/δ regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARβ/δ as a treatment for human metabolic disorders
dc.format.extent14 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec680789
dc.identifier.issn1661-6596
dc.identifier.pmid29558390
dc.identifier.urihttps://hdl.handle.net/2445/157699
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ijms19030913
dc.relation.ispartofInternational Journal of Molecular Sciences, 2018, vol. 19, num. 3, p. 913
dc.relation.urihttps://doi.org/10.3390/ijms19030913
dc.rightscc-by (c) Palomer Tarridas, Francesc Xavier et al., 2018
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationHomeòstasi
dc.subject.classificationObesitat
dc.subject.classificationDiabetis
dc.subject.classificationMetabolisme cel·lular
dc.subject.classificationFarmacologia
dc.subject.otherHomeostasis
dc.subject.otherObesity
dc.subject.otherDiabetes
dc.subject.otherCell metabolism
dc.subject.otherPharmacology
dc.titlePPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)