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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/188623
Study of Matrigel deformation during the formation of 3D tubular networks of intestinal epithelial cells
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Intestinal epithelial cells auto-organize in both three-dimensional (3D) networks and two-dimensional (2D) monolayers depending on the concentration of the extracellular matrix in which they are being grown (Matrigel) causing its deformation. With the use of time lapse videos and fluorescence beads we obtain the velocity fields with a technique called Particle Image Velocimetry. We then use these velocity fields to characterize the rates of deformation with the strain rate tensor. We observe how the magnitudes of the rates of deformation for the high concentration Matrigel are larger than the ones of the low concentration Matrigel which correlates with the observations
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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2022, Tutor: Jordi Comelles Pujadas
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CARO CHACÓN, Alejandro. Study of Matrigel deformation during the formation of 3D tubular networks of intestinal epithelial cells. [consulted: 16 of June of 2026]. Available at: https://hdl.handle.net/2445/188623