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2020-11-09

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cc-by (c) Torres, Ximena et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/176424

Uncomplicated monochorionic twins: two normal hearts sharing one placenta

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Recurs relacionat

https://doi.org/10.3390/jcm9113602

Resum

Cardiovascular dysfunction has been reported in complicated monochorionic diamniotic (MCDA) pregnancies; however, little is known whether hemodynamic changes occur in uncomplicated MCDA twins. A prospective observational study was conducted including 100 uncomplicated MCDA twins matched by gestational age to 200 low-risk singletons. Echocardiography was performed at 26-30 weeks gestation and cord blood B-type natriuretic peptide (BNP) was measured at delivery. In both groups, z-scores for echocardiographic parameters were within normal ranges; however the monochorionic group had larger atrial areas (mean (standard deviation) right atria-to-heart ratio: 17.0 (2) vs. 15.9 (1); p = 0.018; left atria-to-heart ratio: 17.0 (3) vs. 15.8 (2); p < 0.001) and signs of concentric hypertrophy (right relative wall thickness: 0.66 (0.12) vs. 0.56 (0.11); p < 0.001; left relative wall thickness: 0.69 (0.14) vs. 0.58 (0.12); p < 0.001). Longitudinal function was increased in twins, leading to higher tricuspid annular plane systolic excursion (6.9 mm (0.9) vs. 5.9 mm (0.7); p < 0.001) and mitral annular plane systolic excursion (4.9 mm (0.8) vs. 4.4 mm (1.1); p < 0.001. BNP levels at birth were also higher in MCDA twins (median [interquartile range]: 20.81 pg/mL [16.69-34.01] vs. 13.14 pg/mL [9.17-19.84]; p < 0.001). Thus, uncomplicated MCDA fetuses have normal cardiac shape and function, but signs of cardiac adaptation were identified by echocardiographic and biochemical parameters, when compared with singletons.

Matèries

Malalties cardiovasculars, Bessons, Ecocardiografia

Matèries (anglès)

Cardiovascular diseases, Twins, Echocardiography

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Col·leccions

Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)
Articles publicats en revistes (BCNatal Fetal Medicine Research Center)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

TORRES, Ximena, BENNASAR SANS, Mª del mar, GARCÍA OTERO, Laura, MARTÍNEZ PORTILLA, Raigam j., VALENZUELA ALCARAZ, Brenda i., CRISPI BRILLAS, Fàtima, GONCÉ MELLGREN, Anna, GRATACÓS SOLSONA, Eduard, FIGUERAS RETUERTA, Francesc, MARTÍNEZ CRESPO, Josep m. (josep maria). Uncomplicated monochorionic twins: two normal hearts sharing one placenta. _Journal of Clinical Medicine_. 2020. Vol. 9, núm. 11. [consulta: 15 de gener de 2026]. ISSN: 2077-0383. [Disponible a: https://hdl.handle.net/2445/176424]

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