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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/8758
Microinductive signal conditioning with resonant differential filters: high-sensitivity biodetection applications
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Inductive-based devices integrated with Si technology for biodetection applications are characterized, using simple resonant differential filter configurations. This has allowed the corroboration of the viability of the proposed circuits, which are characterized by their very high simplicity, for microinductive signal conditioning in high-sensitivity sensor devices. The simulation of these simple circuits predicts sensitivities of the differential output voltage which can achieve values in the range of 0.1-1 V/nH, depending on the coil parameters. These very high-sensitivity values open the possibility for the experimental detection of extremely small inductance changes in the devices. For real microinductive devices, both series resistance and parasitic capacitive components contribute to the decrease of the differential circuit sensitivity. Nevertheless, measurements performed using micro-coils fabricated with relatively high series resistance and coupling parasitic effects have allowed detection of changes in the range of 2 nH. which are compatible with biodetection applications with estimated detection limits below the picomolarity range.
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BAGLIO, Salvatore, et al. Microinductive signal conditioning with resonant differential filters: high-sensitivity biodetection applications. IEEE Transactions on Instrumentation and Measurement. 2007. Vol. 56, num. 5, pags. 1590-1595. ISSN 0018-9456. [consulted: 10 of June of 2026]. Available at: https://hdl.handle.net/2445/8758