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Treball de fi de grau

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cc-by-nc-nd (c) Mut, 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/171392

Computational analysis of signal dynamics induced by ligands

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Resum

During tissue development, cells differentiate creating a cellular pattern thanks to communication frameworks like the one studied, the Notch signalling pathway. In such mechanisms a cell interacts with the surrounding cells through proteins called ligands. With a numerical simulation program we manage to confirm the formation of cell patterns and doing a lineal stability analysis we find under which conditions the pattern can arise for a sustained signal activation. Furthermore, when implementing a transitory pulsating signal dynamics we find that a minimum interaction time is required if the cells are to differentiate

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutora: Marta Ibañes Miguez

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Citació

MUT SBERT, Macià. Computational analysis of signal dynamics induced by ligands. [consulta: 15 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/171392]

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