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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/127394

A multifunctional toolkit for target-directed cancer therapy

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Here we present 2shRNA, a shRNA-based nanobinder, which can simultaneously attack two therapeutic targets involved in drug resistance pathways and can additionally bind accessory molecules such as cell targeting peptides or fluorophores. We create 2shRNAs designed to specifically kill HER2+ breast cancer cells in the absence of a transfecting agent.

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TERRAZAS MARTÍNEZ, Montserrat, et al. A multifunctional toolkit for target-directed cancer therapy. Chemical Communications. 2018. [consulted: 27 of June of 2026]. Available at: https://hdl.handle.net/2445/127394

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