Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/217673
Microbiota-derived extracellular vesicles in interkingdom communication in the gut
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
The intestine is fundamental in controlling human health. Intestinal epithelial and immune cells are continuously exposed to millions of microbes that greatly impact on intestinal epithelial barrier and immune function. This microbial community, known as gutmicrobiota, is now recognized as an important partner of the human being that actively contribute to essential functions of the intestine but also of distal organs. In the gut ecosystem, bidirectional microbiota-host communication does not involve direct cell contacts. Bothmicrobiota and host-derived extracellular vesicles (EVs) are key players of such interkingdom crosstalk. There is now accumulating body of evidence that bacterial secreted vesicles mediate microbiota functions by transporting and delivering into host cells effector molecules that modulate host signalling pathways and cell processes. Consequently, vesicles released by the gut microbiota may have great influence on health and disease. Here we review current knowledge on microbiota EVs and specifically highlight their role in controlling host metabolism, intestinal barrier integrity and immune training.
Matèries (anglès)
Citació
Citació
DÍAZ GARRIDO, Natalia, BADÍA PALACÍN, Josefa, BALDOMÀ LLAVINÉS, Laura. Microbiota-derived extracellular vesicles in interkingdom communication in the gut. _Journal Of Extracellular Vesicles_. 2021. Vol. 10, núm. e12161. [consulta: 22 de gener de 2026]. ISSN: 2001-3078. [Disponible a: https://hdl.handle.net/2445/217673]